HIT-result

Type	Detail
Target ID	T19HZC
Protein Name	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Uniprot ID	Q9UL51
Protein Name Alias	Brain cyclic nucleotide-gated channel 2; BCNG-2
Gene ID	610
Gene Symbol	HCN2
Gene Alias	BCNG2
TTD	T65005: Research target
Pfam	PF00027 ; PF00520 ; PF08412
GO	0030552:cAMP binding 0071805:potassium ion transmembrane transport 0086012:membrane depolarization during cardiac muscle cell action potential 0098855:HCN channel complex 0005248:voltage-gated sodium channel activity 0042802:identical protein binding 0007267:cell-cell signaling 0005886:plasma membrane 0071320:cellular response to cAMP 0071321:cellular response to cGMP 0042391:regulation of membrane potential 0034765:regulation of ion transmembrane transport 0005887:integral component of plasma membrane 0005222:intracellular cAMP-activated cation channel activity 1990573:potassium ion import across plasma membrane 0008076:voltage-gated potassium channel complex 0098719:sodium ion import across plasma membrane 0035725:sodium ion transmembrane transport 0005249:voltage-gated potassium channel activity
PDB	2MPF ; 3U10
Drugbank	DB02527 ; DB02315 ; DB09083
KEGG	hsa:610

Target Description