Target Description

Type Detail
Target ID T19VO1
Protein Name Peroxiredoxin-6
Uniprot ID P30041
Protein Name Alias EC 1.11.1.27;  1-Cys peroxiredoxin;  1-Cys PRX;  24 kDa protein;  Acidic calcium-independent phospholipase A2;  aiPLA2;  EC 3.1.1.4;  Antioxidant protein 2;  Glutathione-dependent peroxiredoxin;  Liver 2D page spot 40;  Lysophosphatidylcholine acyltransferase 5;  LPC acyltransferase 5;  LPCAT-5;  Lyso-PC acyltransferase 5;  EC 2.3.1.23;  Non-selenium glutathione peroxidase;  NSGPx;  Red blood cells page spot 12
Gene ID 9588
Gene Symbol PRDX6
Gene Alias AOP2;  KIAA0106
TTD NA
Pfam PF10417 ; PF00578
GO
0042802:identical protein binding

0005634:nucleus

0045454:cell redox homeostasis

0048026:positive regulation of mRNA splicing, via spliceosome

0004602:glutathione peroxidase activity

0070062:extracellular exosome

0005829:cytosol

0098869:cellular oxidant detoxification

0031625:ubiquitin protein ligase binding

0004623:phospholipase A2 activity

0034599:cellular response to oxidative stress

0047499:calcium-independent phospholipase A2 activity

0035578:azurophil granule lumen

0046475:glycerophospholipid catabolic process

0005737:cytoplasm

0005615:extracellular space

0047184:1-acylglycerophosphocholine O-acyltransferase activity

0048471:perinuclear region of cytoplasm

0102567:phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)

0043312:neutrophil degranulation

0051920:peroxiredoxin activity

0016020:membrane

0006979:response to oxidative stress

0005576:extracellular region

0005739:mitochondrion

0102568:phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)

0045296:cadherin binding

0042744:hydrogen peroxide catabolic process

PDB 1PRX ; 5B6N ; 5B6M
Drugbank DB03814 ; DB09130
KEGG hsa:9588

Related Compounds  (Total: 1)

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C0456
Name: Tretinoin


Related Herbs  (Total: 2)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens