HIT-result

Target Description

Type	Detail
Target ID	T20N45
Protein Name	Muscle, skeletal receptor tyrosine-protein kinase
Uniprot ID	O15146
Protein Name Alias	EC 2.7.10.1; Muscle-specific tyrosine-protein kinase receptor; MuSK; Muscle-specific kinase receptor
Gene ID	4593
Gene Symbol	MUSK
Gene Alias	NA
TTD	T44387: Research target
Pfam	PF07679 ; PF01392 ; PF07714
GO	0043235:receptor complex 0007275:multicellular organism development 0046777:protein autophosphorylation 2000541:positive regulation of protein geranylgeranylation 0071340:skeletal muscle acetylcholine-gated channel clustering 0038062:protein tyrosine kinase collagen receptor activity 0007169:transmembrane receptor protein tyrosine kinase signaling pathway 0004713:protein tyrosine kinase activity 0008582:regulation of synaptic growth at neuromuscular junction 0005887:integral component of plasma membrane 0045211:postsynaptic membrane 0030154:cell differentiation 0005518:collagen binding 0010628:positive regulation of gene expression 0005524:ATP binding 0001934:positive regulation of protein phosphorylation 0007528:neuromuscular junction development 0004714:transmembrane receptor protein tyrosine kinase activity 0033674:positive regulation of kinase activity 0046872:metal ion binding 0031594:neuromuscular junction 0007613:memory
PDB	NA
Drugbank	DB12010
KEGG	hsa:4593

Type

Detail

Target ID

T20N45

Protein Name

Muscle, skeletal receptor tyrosine-protein kinase

Uniprot ID

O15146

Protein Name Alias

EC 2.7.10.1; Muscle-specific tyrosine-protein kinase receptor; MuSK; Muscle-specific kinase receptor

Gene ID

4593

Gene Symbol

MUSK

Gene Alias

TTD

T44387: Research target

Pfam

PF07679 ; PF01392 ; PF07714

0043235:receptor complex

0007275:multicellular organism development

0046777:protein autophosphorylation

2000541:positive regulation of protein geranylgeranylation

0071340:skeletal muscle acetylcholine-gated channel clustering

0038062:protein tyrosine kinase collagen receptor activity

0007169:transmembrane receptor protein tyrosine kinase signaling pathway

0004713:protein tyrosine kinase activity

0008582:regulation of synaptic growth at neuromuscular junction

0005887:integral component of plasma membrane

0045211:postsynaptic membrane

0030154:cell differentiation

0005518:collagen binding

0010628:positive regulation of gene expression

0005524:ATP binding

0001934:positive regulation of protein phosphorylation

0007528:neuromuscular junction development

0004714:transmembrane receptor protein tyrosine kinase activity

0033674:positive regulation of kinase activity

0046872:metal ion binding

0031594:neuromuscular junction

0007613:memory

PDB

Drugbank

DB12010

KEGG

hsa:4593

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0805	Zhi Ke Gan Jin Gao	枳壳干浸膏	Seville ora nge unripe fruit	Citrus aurantium
H0244	Mi La	蜜蜡	Bee wax	Apis cerana
H0419	Shan Zha	山楂	Chinese hawthorn	Crataegus pinnatifida
H1127	Guang Shan Zha	广山楂	Chinese hawthorn	Crataegus pinnatifida
H0421	Shan Zha Qing Gao	山楂清膏	Chinese hawthorn	Crataegus pinnatifida
H0804	Zhi Ke	枳壳	Seville ora nge unripe fruit	Citrus aurantium
H1040	Feng Mi	蜂蜜	Honey	Apis cerana
H0420	Shan Zha Chou Gao	山楂稠膏	Chinese hawthorn	Crataegus pinnatifida
H0802	Zhi Geng	枳梗	NA	Citrus aurantium
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0961	Dang Yao	当药	Chinese swertia	Swertia chinensis
H0422	Shan Zha Tan	山楂炭	Chinese hawthorn	Crataegus pinnatifida
H0813	Zhi Shi	枳实	Seville orange young fruit	Citrus aurantium
H0758	Cheng Pi	橙皮	Bitter orange	Citrus aurantium
H0166	Long Kui	龙葵	Black nightshade	Solanum nigrum
H0733	Ye Shan Zha	野山楂	nippon bawthorn	Crataegus pinnatifida
H0903	Ci Cai	荠菜	Shepherdspurse	Capsella bursa-pastoris

Target Description

Related Compounds (Total: 1)

Related Herbs (Total: 18)