Compound Description
| ID: C0854 | Common name: Acetylcholine |
| IUPAC: 2-acetyloxyethyl(trimethyl)azanium | CAS: CAS:51-84-3 |
| Chembl ID: CHEMBL667 | Pubchem ID: CID:187 |
| Formula: C7H16NO2 | TCM-ID: TCMC619 |
| Smiles: CC(=O)OCC[N+](C)(C)C | |
| Alias:
Choline acetate (ester);
Choline, acetate; 2-(Acetyloxy)-N,N,N-trimethylethanaminium; ACh; Acetyl choline ion; Acetylcholine; Acetylcholine cation; Acetylcholinium; Choline, acetyl- |
Structure:
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Related Targets (Total: 16)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T25Y64 | Cholinesterase | BCHE |
P06276 |
A | 1 Reference(s) |
| T22H7B | Neuronal acetylcholine receptor subunit alpha-4 | CHRNA4 |
P43681 |
A | 2 Reference(s) |
| T68CKY | Tyrosine-protein kinase Fyn | FYN |
P06241 |
A | 1 Reference(s) |
| T83YZD | Acetylcholinesterase | ACHE |
P22303 |
A | 1 Reference(s) |
| T54B00 | P2X purinoceptor 7 | P2RX7 |
Q99572 |
A | 1 Reference(s) |
| T29MD1 | Mitogen-activated protein kinase 8 | MAPK8 |
P45983 |
C | 1 Reference(s) |
| T25NSJ | Mitogen-activated protein kinase 3 | MAPK3 |
P27361 |
C | 2 Reference(s) |
| T79WXA | Mitogen-activated protein kinase 1 | MAPK1 |
P28482 |
C | 1 Reference(s) |
| T86ROZ | Heme oxygenase 1 | HMOX1 |
P09601 |
C | 1 Reference(s) |
| T53AOE | Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide | TGFB1 |
P01137 |
C | 1 Reference(s) |
| T17FIA | Angiotensinogen | AGT |
P01019 |
C | 1 Reference(s) |
| T68BGR | Glial fibrillary acidic protein | GFAP |
P14136 |
C | 1 Reference(s) |
| T20N45 | Muscle, skeletal receptor tyrosine-protein kinase | MUSK |
O15146 |
C | 1 Reference(s) |
| T79O0V | Beta-3 adrenergic receptor | ADRB3 |
P13945 |
C | 1 Reference(s) |
| T24WXZ | NA | GAS5 |
NA |
C | 1 Reference(s) |
| T33OPP | Interleukin-6 | IL6 |
P05231 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 18)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0805 | Zhi Ke Gan Jin Gao | 枳壳干浸膏 | Seville ora nge unripe fruit | Citrus aurantium |
| H0244 | Mi La | 蜜蜡 | Bee wax | Apis cerana |
| H0419 | Shan Zha | 山楂 | Chinese hawthorn | Crataegus pinnatifida |
| H1127 | Guang Shan Zha | 广山楂 | Chinese hawthorn | Crataegus pinnatifida |
| H0421 | Shan Zha Qing Gao | 山楂清膏 | Chinese hawthorn | Crataegus pinnatifida |
| H0804 | Zhi Ke | 枳壳 | Seville ora nge unripe fruit | Citrus aurantium |
| H1040 | Feng Mi | 蜂蜜 | Honey | Apis cerana |
| H0420 | Shan Zha Chou Gao | 山楂稠膏 | Chinese hawthorn | Crataegus pinnatifida |
| H0802 | Zhi Geng | 枳梗 | NA | Citrus aurantium |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0961 | Dang Yao | 当药 | Chinese swertia | Swertia chinensis |
| H0422 | Shan Zha Tan | 山楂炭 | Chinese hawthorn | Crataegus pinnatifida |
| H0813 | Zhi Shi | 枳实 | Seville orange young fruit | Citrus aurantium |
| H0758 | Cheng Pi | 橙皮 | Bitter orange | Citrus aurantium |
| H0166 | Long Kui | 龙葵 | Black nightshade | Solanum nigrum |
| H0733 | Ye Shan Zha | 野山楂 | nippon bawthorn | Crataegus pinnatifida |
| H0903 | Ci Cai | 荠菜 | Shepherdspurse | Capsella bursa-pastoris |
Ckey description of the interaction between compound and target