HIT-result

Type	Detail
Target ID	T21MT2
Protein Name	Nuclear factor of activated T-cells 5
Uniprot ID	O94916
Protein Name Alias	NF-AT5; T-cell transcription factor NFAT5; Tonicity-responsive enhancer-binding protein; TonE-binding protein; TonEBP
Gene ID	10725
Gene Symbol	NFAT5
Gene Alias	KIAA0827; TONEBP
TTD	NA
Pfam	PF00554 ; PF16179
GO	0005667:transcription regulator complex 1901224:positive regulation of NIK/NF-kappaB signaling 1990837:sequence-specific double-stranded DNA binding 0008134:transcription factor binding 0006970:response to osmotic stress 0005829:cytosol 0071345:cellular response to cytokine stimulus 0001228:DNA-binding transcription activator activity, RNA polymerase II-specific 0033173:calcineurin-NFAT signaling cascade 0005654:nucleoplasm 1904996:positive regulation of leukocyte adhesion to vascular endothelial cell 0000785:chromatin 0070884:regulation of calcineurin-NFAT signaling cascade 0003700:DNA-binding transcription factor activity 0045944:positive regulation of transcription by RNA polymerase II 0007588:excretion 0005634:nucleus 0006366:transcription by RNA polymerase II 0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding 0007165:signal transduction 0000981:DNA-binding transcription factor activity, RNA polymerase II-specific 0006357:regulation of transcription by RNA polymerase II
PDB	1IMH
Drugbank	NA
KEGG	hsa:10725

Target Description