HIT-result

Type	Detail
Target ID	T21O8C
Protein Name	Coagulation factor XII
Uniprot ID	P00748
Protein Name Alias	EC 3.4.21.38; Hageman factor; HAF
Gene ID	2161
Gene Symbol	F12
Gene Alias	NA
TTD	T38509: Clinical Trial target
Pfam	PF00039 ; PF00008 ; PF00089 ; PF00040 ; PF00051
GO	0042730:fibrinolysis 0070062:extracellular exosome 0006508:proteolysis 0051787:misfolded protein binding 0002542:Factor XII activation 0007597:blood coagulation, intrinsic pathway 0030194:positive regulation of blood coagulation 0051919:positive regulation of fibrinolysis 0005509:calcium ion binding 0005615:extracellular space 0010756:positive regulation of plasminogen activation 0007596:blood coagulation 0005886:plasma membrane 2000267:negative regulation of blood coagulation, intrinsic pathway 0051788:response to misfolded protein 0062023:collagen-containing extracellular matrix 0005576:extracellular region 0016485:protein processing 0005791:rough endoplasmic reticulum 0016540:protein autoprocessing 0004252:serine-type endopeptidase activity 0002353:plasma kallikrein-kinin cascade 0045087:innate immune response 0031638:zymogen activation
PDB	6SZW ; 6L63 ; 4BDX ; 4XDE ; 4XE4 ; 6B74 ; 6GT6 ; 6QF7 ; 4BDW ; 6B77
Drugbank	DB12598 ; DB01593 ; DB09228 ; DB06404 ; DB06689 ; DB14487
KEGG	hsa:2161

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens

Target Description