Target Description

Type Detail
Target ID T22XVR
Protein Name Transcription factor PU.1
Uniprot ID P17947
Protein Name Alias 31 kDa-transforming protein
Gene ID 6688
Gene Symbol SPI1
Gene Alias NA
TTD NA
Pfam PF00178
GO
0045814:negative regulation of gene expression, epigenetic

1902895:positive regulation of pri-miRNA transcription by RNA polymerase II

0000987:cis-regulatory region sequence-specific DNA binding

0005654:nucleoplasm

0002357:defense response to tumor cell

0031663:lipopolysaccharide-mediated signaling pathway

0000976:transcription regulatory region sequence-specific DNA binding

0001228:DNA-binding transcription activator activity, RNA polymerase II-specific

0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding

0002316:follicular B cell differentiation

0003700:DNA-binding transcription factor activity

0003682:chromatin binding

0034401:chromatin organization involved in regulation of transcription

0044027:hypermethylation of CpG island

0098508:endothelial to hematopoietic transition

1904178:negative regulation of adipose tissue development

1901674:regulation of histone H3-K27 acetylation

0002572:pro-T cell differentiation

1905036:positive regulation of antifungal innate immune response

0032088:negative regulation of NF-kappaB transcription factor activity

0001217:DNA-binding transcription repressor activity

0043966:histone H3 acetylation

0010629:negative regulation of gene expression

0045893:positive regulation of transcription, DNA-templated

0036462:TRAIL-activated apoptotic signaling pathway

0000122:negative regulation of transcription by RNA polymerase II

0030225:macrophage differentiation

1904151:positive regulation of microglial cell mediated cytotoxicity

1900745:positive regulation of p38MAPK cascade

0090241:negative regulation of histone H4 acetylation

0045892:negative regulation of transcription, DNA-templated

0000785:chromatin

0030218:erythrocyte differentiation

0045646:regulation of erythrocyte differentiation

0006357:regulation of transcription by RNA polymerase II

0005667:transcription regulator complex

0001085:RNA polymerase II transcription factor binding

0002314:germinal center B cell differentiation

0005634:nucleus

0008134:transcription factor binding

0120186:negative regulation of protein localization to chromatin

0043314:negative regulation of neutrophil degranulation

0042826:histone deacetylase binding

0001227:DNA-binding transcription repressor activity, RNA polymerase II-specific

0002573:myeloid leukocyte differentiation

1901223:negative regulation of NIK/NF-kappaB signaling

0002327:immature B cell differentiation

0070102:interleukin-6-mediated signaling pathway

0090402:oncogene-induced cell senescence

0006355:regulation of transcription, DNA-templated

2000529:positive regulation of myeloid dendritic cell chemotaxis

0030154:cell differentiation

1902262:apoptotic process involved in blood vessel morphogenesis

0051090:regulation of DNA-binding transcription factor activity

0045347:negative regulation of MHC class II biosynthetic process

1905453:regulation of myeloid progenitor cell differentiation

0007179:transforming growth factor beta receptor signaling pathway

0001216:DNA-binding transcription activator activity

0000981:DNA-binding transcription factor activity, RNA polymerase II-specific

0003723:RNA binding

1904238:pericyte cell differentiation

0140297:DNA-binding transcription factor binding

0045944:positive regulation of transcription by RNA polymerase II

0060033:anatomical structure regression

0140311:protein sequestering activity

0043011:myeloid dendritic cell differentiation

0051525:NFAT protein binding

0030851:granulocyte differentiation

0071361:cellular response to ethanol

0035019:somatic stem cell population maintenance

PDB NA
Drugbank NA
KEGG hsa:6688

Related Compounds  (Total: 1)

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C1214
Name: Capsaicin


Related Herbs  (Total: 8)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0242 Bei Sha Shen Liu Jin Gao北沙参流浸膏 Glehnia littoralisGlehnia littoralis
H0239 Bei Sha Shen北沙参 Coastal glehniaGlehnia littoralis
H0123 La Jiao Liu Jin Gao辣椒流浸膏 Bush redpepperCapsicum frutescens
H0227 Mang Guo Ye芒果叶 Mango leafMangifera indica
H0121 La Jiao Jin Chu Ye辣椒浸出液 Bush redpepperCapsicum frutescens
H0122 La Jiao Jin Gao辣椒浸膏 Bush redpepperCapsicum frutescens
H0854 Zi Wei Gen Pi紫葳根皮 NACampsis grandiflora
H0119 La Jiao辣椒 Bush redpepperCapsicum frutescens