HIT-result

Type	Detail
Target ID	T23FEE
Protein Name	Hepatocyte nuclear factor 3-beta
Uniprot ID	Q9Y261
Protein Name Alias	HNF-3-beta; HNF-3B; Forkhead box protein A2; Transcription factor 3B; TCF-3B
Gene ID	3170
Gene Symbol	FOXA2
Gene Alias	HNF3B; TCF3B
TTD	NA
Pfam	PF08430 ; PF09354 ; PF00250
GO	0003677:DNA binding 0008134:transcription factor binding 0005634:nucleus 0010719:negative regulation of epithelial to mesenchymal transition 2000971:negative regulation of detection of glucose 0070741:response to interleukin-6 0031018:endocrine pancreas development 0019904:protein domain specific binding 2000049:positive regulation of cell-cell adhesion mediated by cadherin 0033132:negative regulation of glucokinase activity 0009653:anatomical structure morphogenesis 0071542:dopaminergic neuron differentiation 0005737:cytoplasm 0030154:cell differentiation 0061987:negative regulation of transcription from RNA polymerase II promoter by glucose 0030054:cell junction 0061178:regulation of insulin secretion involved in cellular response to glucose stimulus 0000785:chromatin 0000432:positive regulation of transcription from RNA polymerase II promoter by glucose 0000976:transcription regulatory region sequence-specific DNA binding 0090009:primitive streak formation 0000981:DNA-binding transcription factor activity, RNA polymerase II-specific 0045893:positive regulation of transcription, DNA-templated 0043433:negative regulation of DNA-binding transcription factor activity 0003700:DNA-binding transcription factor activity 2000543:positive regulation of gastrulation 0006357:regulation of transcription by RNA polymerase II 0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding 0005654:nucleoplasm 1990837:sequence-specific double-stranded DNA binding 0008344:adult locomotory behavior 0001708:cell fate specification 0045944:positive regulation of transcription by RNA polymerase II 0040019:positive regulation of embryonic development 0030193:regulation of blood coagulation 0006325:chromatin organization
PDB	5X07
Drugbank	NA
KEGG	hsa:3170

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Name: Bile Acid

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0431	She Dan Zhi	蛇胆汁	Snake bile	Fel serpentis liquidum