HIT-result

Type	Detail
Target ID	T26QPN
Protein Name	Maternal embryonic leucine zipper kinase
Uniprot ID	Q14680
Protein Name Alias	hMELK; EC 2.7.11.1; Protein kinase Eg3; pEg3 kinase; Protein kinase PK38; hPK38; Tyrosine-protein kinase MELK; EC 2.7.10.2
Gene ID	9833
Gene Symbol	MELK
Gene Alias	KIAA0175
TTD	T61518: Clinical Trial target
Pfam	PF00069 ; PF02149
GO	0005634:nucleus 0046777:protein autophosphorylation 0035556:intracellular signal transduction 0005938:cell cortex 0106310:protein serine kinase activity 0004674:protein serine/threonine kinase activity 0008631:intrinsic apoptotic signaling pathway in response to oxidative stress 0106311:protein threonine kinase activity 0006915:apoptotic process 0005737:cytoplasm 0005509:calcium ion binding 0005524:ATP binding 0005886:plasma membrane 0016020:membrane 0030097:hemopoiesis 0004715:non-membrane spanning protein tyrosine kinase activity 0043065:positive regulation of apoptotic process 0006468:protein phosphorylation 0004714:transmembrane receptor protein tyrosine kinase activity 0061351:neural precursor cell proliferation 0000086:G2/M transition of mitotic cell cycle 0008283:cell population proliferation 0008289:lipid binding
PDB	5TWU ; 4UMQ ; 4UMP ; 5IH8 ; 4BKY ; 5IHA ; 4D2P ; 5TWZ ; 5MAI ; 5TVT ; 6VXR ; 5TX3 ; 5M5A ; 5TWY ; 5MAH ; 4UMT ; 5MAF ; 5IHC ; 5K00 ; 4BL1 ; 5IH9 ; 4IXP ; 6GVX ; 4D2V ; 5MAG ; 4UMU ; 4UMR ; 4D2W ; 4BKZ ; 5TWL ; 4D2T
Drugbank	DB12010
KEGG	hsa:9833

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0515	Suan Shi Liu	酸石榴	Pomegranate	Punica granatum
H0462	Shi Liu	石榴	Pomegranate fruit	Punica granatum
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0463	Shi Liu Pi	石榴皮	Pomegranate peel	Punica granatum
H0464	Shi Liu Zi	石榴子	NA	Punica granatum

Target Description