HIT-result

Type	Detail
Target ID	T28IL8
Protein Name	D(1A) dopamine receptor
Uniprot ID	P21728
Protein Name Alias	Dopamine D1 receptor
Gene ID	1812
Gene Symbol	DRD1
Gene Alias	NA
TTD	T22118: Successful target
Pfam	PF00001
GO	0060170:ciliary membrane 0007191:adenylate cyclase-activating dopamine receptor signaling pathway 0051584:regulation of dopamine uptake involved in synaptic transmission 0042417:dopamine metabolic process 0005789:endoplasmic reticulum membrane 0042493:response to drug 0051482:positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway 0007187:G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger 0060158:phospholipase C-activating dopamine receptor signaling pathway 0002862:negative regulation of inflammatory response to antigenic stimulus 0043197:dendritic spine 0043268:positive regulation of potassium ion transport 0007212:dopamine receptor signaling pathway 0007186:G protein-coupled receptor signaling pathway 1903351:cellular response to dopamine 0042311:vasodilation 0060134:prepulse inhibition 0071870:cellular response to catecholamine stimulus 0004952:dopamine neurotransmitter receptor activity 0007628:adult walking behavior 0005929:cilium 0005886:plasma membrane 0004930:G protein-coupled receptor activity 0035240:dopamine binding 0019226:transmission of nerve impulse 0007617:mating behavior 0007416:synapse assembly 0005887:integral component of plasma membrane 0021853:cerebral cortex GABAergic interneuron migration 0051968:positive regulation of synaptic transmission, glutamatergic 0051281:positive regulation of release of sequestered calcium ion into cytosol 0030335:positive regulation of cell migration 0071880:adenylate cyclase-activating adrenergic receptor signaling pathway 0001588:dopamine neurotransmitter receptor activity, coupled via Gs 0010628:positive regulation of gene expression 0097730:non-motile cilium 0007190:activation of adenylate cyclase activity 0008542:visual learning 0007189:adenylate cyclase-activating G protein-coupled receptor signaling pathway
PDB	1OZ5
Drugbank	DB01186 ; DB01608 ; DB00714 ; DB06148 ; DB00734 ; DB01622 ; DB00679 ; DB05271 ; DB09097 ; DB00502 ; DB01038 ; DB01200 ; DB01614 ; DB00543 ; DB00458 ; DB00589 ; DB11275 ; DB11584 ; DB01621 ; DB00477 ; DB00623 ; DB01239 ; DB00363 ; DB04946 ; DB00408 ; DB09286 ; DB00555 ; DB01624 ; DB12093 ; DB01049 ; DB09225 ; DB00353 ; DB06216 ; DB00508 ; DB14185 ; DB00568 ; DB00850 ; DB00726 ; DB00988 ; DB01623 ; DB00334 ; DB11274 ; DB00397 ; DB12890 ; DB00248 ; DB00875 ; DB00805 ; DB01403 ; DB00715 ; DB13345 ; DB00696 ; DB00800 ; DB01224 ; DB01238 ; DB01235 ; DB06077 ; DB01267 ; DB00246
KEGG	hsa:1812

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Name: Stepholidine

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Name: cocaine

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0369	Bian Fu Ge	蝙蝠葛	Asiatic moonseed	Menispermum dauricum
H0341	Qing Feng Teng	青风藤	Orientvine	Sinomenium acutum
H0941	Da Zao	大枣	Chinese date	Ziziphus jujuba