Target Description

Type Detail
Target ID T28TAQ
Protein Name Large neutral amino acids transporter small subunit 1
Uniprot ID Q01650
Protein Name Alias 4F2 light chain;  4F2 LC;  4F2LC;  CD98 light chain;  Integral membrane protein E16;  E16;  L-type amino acid transporter 1;  hLAT1;  Solute carrier family 7 member 5;  y+ system cationic amino acid transporter
Gene ID 8140
Gene Symbol SLC7A5
Gene Alias CD98LC;  LAT1;  MPE16
TTD T48330: Research target
Pfam PF13520
GO
0070062:extracellular exosome

0098591:external side of apical plasma membrane

0015190:L-leucine transmembrane transporter activity

0015173:aromatic amino acid transmembrane transporter activity

0010629:negative regulation of gene expression

0016021:integral component of membrane

0150104:transport across blood-brain barrier

0016020:membrane

0050900:leukocyte migration

0015171:amino acid transmembrane transporter activity

0098713:leucine import across plasma membrane

0015179:L-amino acid transmembrane transporter activity

1903801:L-leucine import across plasma membrane

0042908:xenobiotic transport

0031528:microvillus membrane

1990184:amino acid transport complex

0005829:cytosol

0015349:thyroid hormone transmembrane transporter activity

0032729:positive regulation of interferon-gamma production

0032753:positive regulation of interleukin-4 production

0005886:plasma membrane

0005765:lysosomal membrane

1902475:L-alpha-amino acid transmembrane transport

0015804:neutral amino acid transport

0015823:phenylalanine transport

0016323:basolateral plasma membrane

0015196:L-tryptophan transmembrane transporter activity

0070327:thyroid hormone transport

0089718:amino acid import across plasma membrane

0009925:basal plasma membrane

0032740:positive regulation of interleukin-17 production

0042605:peptide antigen binding

0043231:intracellular membrane-bounded organelle

0015175:neutral amino acid transmembrane transporter activity

0002720:positive regulation of cytokine production involved in immune response

1904556:L-tryptophan transmembrane transport

0016324:apical plasma membrane

PDB 6JMQ ; 6IRT ; 6IRS
Drugbank DB00451 ; DB00279 ; DB02750 ; DB09100 ; DB00996 ; DB00130 ; DB01042 ; DB00230 ; DB02556 ; DB01746 ; DB00509 ; DB01235
KEGG hsa:8140

Related Compounds  (Total: 2)

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C0571
Name: Dopa
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C0948
Name: aldosterone


Related Herbs  (Total: 1)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0195 Ma Chi Xian马齿苋 PurslanePortulaca oleracea