HIT-result

Type	Detail
Target ID	T33S3M
Protein Name	Regulator of G-protein signaling 2
Uniprot ID	P41220
Protein Name Alias	RGS2; Cell growth-inhibiting gene 31 protein; G0/G1 switch regulatory protein 8
Gene ID	5997
Gene Symbol	RGS2
Gene Alias	G0S8
TTD	T38325: Research target
Pfam	PF00615
GO	0060452:positive regulation of cardiac muscle contraction 0055119:relaxation of cardiac muscle 0001965:G-protein alpha-subunit binding 0005730:nucleolus 0030728:ovulation 0043951:negative regulation of cAMP-mediated signaling 0007420:brain development 0007186:G protein-coupled receptor signaling pathway 0005096:GTPase activator activity 0005829:cytosol 0140194:negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process 0005516:calmodulin binding 0061052:negative regulation of cell growth involved in cardiac muscle cell development 0007283:spermatogenesis 0005886:plasma membrane 0005737:cytoplasm 0010614:negative regulation of cardiac muscle hypertrophy 0060135:maternal process involved in female pregnancy 0060087:relaxation of vascular associated smooth muscle 0043005:neuron projection 0043407:negative regulation of MAP kinase activity 0010519:negative regulation of phospholipase activity 0050873:brown fat cell differentiation 1900924:negative regulation of glycine import across plasma membrane 0007049:cell cycle 0005739:mitochondrion 0001975:response to amphetamine 0008277:regulation of G protein-coupled receptor signaling pathway 0005634:nucleus 0045744:negative regulation of G protein-coupled receptor signaling pathway 0048487:beta-tubulin binding 0010976:positive regulation of neuron projection development 0017148:negative regulation of translation 0009898:cytoplasmic side of plasma membrane 0045471:response to ethanol
PDB	4EKC ; 2AF0 ; 2V4Z ; 4EKD
Drugbank	NA
KEGG	hsa:5997

Target Description

Related Compounds (Total: 1)

Related Herbs (Total: 0)