Target Description

Type Detail
Target ID T34ON0
Protein Name Endothelin-2
Uniprot ID P20800
Protein Name Alias ET-2;  Preproendothelin-2;  PPET2
Gene ID 1907
Gene Symbol EDN2
Gene Alias NA
TTD T48358: Research target
Pfam PF00322
GO
0014824:artery smooth muscle contraction

0003099:positive regulation of the force of heart contraction by chemical signal

0005576:extracellular region

0007204:positive regulation of cytosolic calcium ion concentration

0019229:regulation of vasoconstriction

0008284:positive regulation of cell population proliferation

0003058:hormonal regulation of the force of heart contraction

0005615:extracellular space

0048016:inositol phosphate-mediated signaling

0042310:vasoconstriction

0006874:cellular calcium ion homeostasis

0001659:temperature homeostasis

0005179:hormone activity

0031708:endothelin B receptor binding

0048286:lung alveolus development

0045987:positive regulation of smooth muscle contraction

0048246:macrophage chemotaxis

0001516:prostaglandin biosynthetic process

0042116:macrophage activation

0007186:G protein-coupled receptor signaling pathway

0019722:calcium-mediated signaling

0060585:positive regulation of prostaglandin-endoperoxide synthase activity

0019221:cytokine-mediated signaling pathway

0007166:cell surface receptor signaling pathway

0002690:positive regulation of leukocyte chemotaxis

0030593:neutrophil chemotaxis

0097009:energy homeostasis

0014826:vein smooth muscle contraction

0010460:positive regulation of heart rate

0003100:regulation of systemic arterial blood pressure by endothelin

PDB NA
Drugbank NA
KEGG hsa:1907

Related Compounds  (Total: 1)

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C0325
Name: Progesterone


Related Herbs  (Total: 8)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0354 Ren Dong Teng忍冬藤 Japanese honeysuckle vineLonicera japonica
H0370 Ru Xiang乳香 OlibanumBoswellia carterii
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0064 Jin Yin Hua金银花 Japanese honeysuckleLonicera japonica
H0065 Jin Yin Hua Ti Qu Ye金银花提取液 Japanese honeysuckleLonicera japonica
H0697 Ya Ma Zi亚麻子 Common flax seedLinum usitatissimum
H0035 Bai Su Zi白苏子 Common perilla fruitPerilla frutescens
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens