Target Description

Type Detail
Target ID T36U0M
Protein Name Neuropilin-1
Uniprot ID O14786
Protein Name Alias Vascular endothelial cell growth factor 165 receptor;  CD antigen CD304
Gene ID 8829
Gene Symbol NRP1
Gene Alias NRP;  VEGF165R
TTD T15023: Successful target
Pfam PF00754 ; PF00431 ; PF11980 ; PF00629
2000251:positive regulation of actin cytoskeleton reorganization

0050918:positive chemotaxis

0048008:platelet-derived growth factor receptor signaling pathway

0043235:receptor complex

0005925:focal adhesion

0006930:substrate-dependent cell migration, cell extension

0009887:animal organ morphogenesis

1902946:protein localization to early endosome

0032489:regulation of Cdc42 protein signal transduction

0097490:sympathetic neuron projection extension

0097491:sympathetic neuron projection guidance

0043005:neuron projection

0031532:actin cytoskeleton reorganization

0043542:endothelial cell migration

0001764:neuron migration

0019838:growth factor binding

0007165:signal transduction

0097102:endothelial tip cell fate specification

0009986:cell surface

0035767:endothelial cell chemotaxis

0019955:cytokine binding

1902336:positive regulation of retinal ganglion cell axon guidance

0038190:VEGF-activated neuropilin signaling pathway

0031966:mitochondrial membrane

1902285:semaphorin-plexin signaling pathway involved in neuron projection guidance

0021675:nerve development


0048844:artery morphogenesis

0005886:plasma membrane

0008201:heparin binding

0097475:motor neuron migration

0007411:axon guidance


0014911:positive regulation of smooth muscle cell migration

0050731:positive regulation of peptidyl-tyrosine phosphorylation

0002116:semaphorin receptor complex

0060385:axonogenesis involved in innervation

1901166:neural crest cell migration involved in autonomic nervous system development

0060978:angiogenesis involved in coronary vascular morphogenesis

0048012:hepatocyte growth factor receptor signaling pathway

0051496:positive regulation of stress fiber assembly

0015026:coreceptor activity

0010595:positive regulation of endothelial cell migration

0030426:growth cone

0017154:semaphorin receptor activity

0046718:viral entry into host cell

0048842:positive regulation of axon extension involved in axon guidance

0046872:metal ion binding

0005769:early endosome

0038085:vascular endothelial growth factor binding

0016021:integral component of membrane

0061549:sympathetic ganglion development

0043025:neuronal cell body

0150020:basal dendrite arborization

0048846:axon extension involved in axon guidance

0042327:positive regulation of phosphorylation

0005021:vascular endothelial growth factor-activated receptor activity

0007229:integrin-mediated signaling pathway

0001569:branching involved in blood vessel morphogenesis

0038189:neuropilin signaling pathway

0048010:vascular endothelial growth factor receptor signaling pathway

0150018:basal dendrite development

0003148:outflow tract septum morphogenesis

0031410:cytoplasmic vesicle

0005615:extracellular space

0070374:positive regulation of ERK1 and ERK2 cascade

0060301:positive regulation of cytokine activity

0002042:cell migration involved in sprouting angiogenesis

0090259:regulation of retinal ganglion cell axon guidance

0048843:negative regulation of axon extension involved in axon guidance

0007267:cell-cell signaling

1900026:positive regulation of substrate adhesion-dependent cell spreading

0005096:GTPase activator activity

0051491:positive regulation of filopodium assembly


0009611:response to wounding

0071526:semaphorin-plexin signaling pathway

0060627:regulation of vesicle-mediated transport

0061299:retina vasculature morphogenesis in camera-type eye

0035924:cellular response to vascular endothelial growth factor stimulus

0034446:substrate adhesion-dependent cell spreading

0035729:cellular response to hepatocyte growth factor stimulus

0071679:commissural neuron axon guidance

0031290:retinal ganglion cell axon guidance

0001938:positive regulation of endothelial cell proliferation

0051894:positive regulation of focal adhesion assembly

0002040:sprouting angiogenesis

0097443:sorting endosome

PDB 6FMF ; 7JJC ; 6FMC ; 5JGQ ; 5JHK ; 5J1X ; 2QQN ; 5C7G ; 2QQI ; 4RN5 ; 2QQM ; 5IYY ; 6TKK ; 5IJR ; 5JGI ; 1KEX ; 3I97 ; 5L73 ; 4DEQ
Drugbank NA
KEGG hsa:8829

Related Compounds  (Total: 1)

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Name: Capsaicin

Related Herbs  (Total: 8)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0227 Mang Guo Ye芒果叶 Mango leafMangifera indica
H0121 La Jiao Jin Chu Ye辣椒浸出液 Bush redpepperCapsicum frutescens
H0122 La Jiao Jin Gao辣椒浸膏 Bush redpepperCapsicum frutescens
H0242 Bei Sha Shen Liu Jin Gao北沙参流浸膏 Glehnia littoralisGlehnia littoralis
H0119 La Jiao辣椒 Bush redpepperCapsicum frutescens
H0239 Bei Sha Shen北沙参 Coastal glehniaGlehnia littoralis
H0854 Zi Wei Gen Pi紫葳根皮 NACampsis grandiflora
H0123 La Jiao Liu Jin Gao辣椒流浸膏 Bush redpepperCapsicum frutescens