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Target Description
Type
Detail
Target ID
T39JB4
Protein Name
Annexin A1
Uniprot ID
P04083
Protein Name Alias
Annexin I; Annexin-1; Calpactin II; Calpactin-2; Chromobindin-9; Lipocortin I; Phospholipase A2 inhibitory protein; p35
Gene ID
301
Gene Symbol
ANXA1
Gene Alias
ANX1; LPC1
TTD
T38161: Successful target
Pfam
PF00191
GO
0010165:response to X-ray
0043434:response to peptide hormone
0090303:positive regulation of wound healing
0035924:cellular response to vascular endothelial growth factor stimulus
0001780:neutrophil homeostasis
0050482:arachidonic acid secretion
0031340:positive regulation of vesicle fusion
0032717:negative regulation of interleukin-8 production
0071385:cellular response to glucocorticoid stimulus
0018149:peptide cross-linking
0006954:inflammatory response
0071621:granulocyte chemotaxis
0045627:positive regulation of T-helper 1 cell differentiation
0005576:extracellular region
0042629:mast cell granule
0032508:DNA duplex unwinding
0007186:G protein-coupled receptor signaling pathway
0001891:phagocytic cup
0003727:single-stranded RNA binding
0043066:negative regulation of apoptotic process
0070365:hepatocyte differentiation
0097060:synaptic membrane
0045087:innate immune response
0030850:prostate gland development
0042802:identical protein binding
0042102:positive regulation of T cell proliferation
0031394:positive regulation of prostaglandin biosynthetic process
0046883:regulation of hormone secretion
0062023:collagen-containing extracellular matrix
0031018:endocrine pancreas development
0005829:cytosol
0050709:negative regulation of protein secretion
0030216:keratinocyte differentiation
0016324:apical plasma membrane
0005737:cytoplasm
0005509:calcium ion binding
0070555:response to interleukin-1
0005615:extracellular space
0006909:phagocytosis
0005912:adherens junction
0019834:phospholipase A2 inhibitor activity
0002548:monocyte chemotaxis
0008360:regulation of cell shape
0019898:extrinsic component of membrane
0031901:early endosome membrane
0005544:calcium-dependent phospholipid binding
0046632:alpha-beta T cell differentiation
0016328:lateral plasma membrane
0045629:negative regulation of T-helper 2 cell differentiation
0005768:endosome
0005634:nucleus
0014839:myoblast migration involved in skeletal muscle regeneration
0098641:cadherin binding involved in cell-cell adhesion
0009986:cell surface
0032652:regulation of interleukin-1 production
1900087:positive regulation of G1/S transition of mitotic cell cycle
0005543:phospholipid binding
0007187:G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
0031313:extrinsic component of endosome membrane
1990814:DNA/DNA annealing activity
0032355:response to estradiol
0031966:mitochondrial membrane
0042493:response to drug
0070459:prolactin secretion
0005102:signaling receptor binding
0003697:single-stranded DNA binding
0031532:actin cytoskeleton reorganization
0042383:sarcolemma
0048306:calcium-dependent protein binding
0050727:regulation of inflammatory response
0001533:cornified envelope
0036121:double-stranded DNA helicase activity
0033031:positive regulation of neutrophil apoptotic process
0070062:extracellular exosome
0070301:cellular response to hydrogen peroxide
0005925:focal adhesion
0002250:adaptive immune response
0045920:negative regulation of exocytosis
0030073:insulin secretion
0030659:cytoplasmic vesicle membrane
0005886:plasma membrane
1900138:negative regulation of phospholipase A2 activity
0031232:extrinsic component of external side of plasma membrane
0031982:vesicle
0032743:positive regulation of interleukin-2 production
0032991:protein-containing complex
0007165:signal transduction
0005654:nucleoplasm
0097350:neutrophil clearance
0042063:gliogenesis
0019221:cytokine-mediated signaling pathway
0016323:basolateral plasma membrane
0007166:cell surface receptor signaling pathway
0031514:motile cilium
0090050:positive regulation of cell migration involved in sprouting angiogenesis
0002685:regulation of leukocyte migration
PDB
5VFW
;
1BO9
;
1QLS
;
1AIN
Drugbank
DB14541
;
DB00591
;
DB14669
;
DB14542
;
DB14538
;
DB14543
;
DB14539
;
DB14631
;
DB00288
;
DB14649
;
DB14540
;
DB00741
;
DB01013
;
DB14544
;
DB01222
;
DB00959
;
DB01234
KEGG
hsa:301
Related Compounds (Total: 1)
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C0456
Name: Tretinoin
Related Herbs (Total: 2)
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Herb id
Chinese Pin Yin
Chinese Character
English Name
Latin Name
H0360
Ren Zhong Bai
人中白
Human urine sediment
Homo sapiens
H0847
Zi He Che
紫河车
Human placenta
Homo sapiens