Target Description

Type Detail
Target ID T39JB4
Protein Name Annexin A1
Uniprot ID P04083
Protein Name Alias Annexin I;  Annexin-1;  Calpactin II;  Calpactin-2;  Chromobindin-9;  Lipocortin I;  Phospholipase A2 inhibitory protein;  p35
Gene ID 301
Gene Symbol ANXA1
Gene Alias ANX1;  LPC1
TTD T38161: Successful target
Pfam PF00191
GO
0010165:response to X-ray

0043434:response to peptide hormone

0090303:positive regulation of wound healing

0035924:cellular response to vascular endothelial growth factor stimulus

0001780:neutrophil homeostasis

0050482:arachidonic acid secretion

0031340:positive regulation of vesicle fusion

0032717:negative regulation of interleukin-8 production

0071385:cellular response to glucocorticoid stimulus

0018149:peptide cross-linking

0006954:inflammatory response

0071621:granulocyte chemotaxis

0045627:positive regulation of T-helper 1 cell differentiation

0005576:extracellular region

0042629:mast cell granule

0032508:DNA duplex unwinding

0007186:G protein-coupled receptor signaling pathway

0001891:phagocytic cup

0003727:single-stranded RNA binding

0043066:negative regulation of apoptotic process

0070365:hepatocyte differentiation

0097060:synaptic membrane

0045087:innate immune response

0030850:prostate gland development

0042802:identical protein binding

0042102:positive regulation of T cell proliferation

0031394:positive regulation of prostaglandin biosynthetic process

0046883:regulation of hormone secretion

0062023:collagen-containing extracellular matrix

0031018:endocrine pancreas development

0005829:cytosol

0050709:negative regulation of protein secretion

0030216:keratinocyte differentiation

0016324:apical plasma membrane

0005737:cytoplasm

0005509:calcium ion binding

0070555:response to interleukin-1

0005615:extracellular space

0006909:phagocytosis

0005912:adherens junction

0019834:phospholipase A2 inhibitor activity

0002548:monocyte chemotaxis

0008360:regulation of cell shape

0019898:extrinsic component of membrane

0031901:early endosome membrane

0005544:calcium-dependent phospholipid binding

0046632:alpha-beta T cell differentiation

0016328:lateral plasma membrane

0045629:negative regulation of T-helper 2 cell differentiation

0005768:endosome

0005634:nucleus

0014839:myoblast migration involved in skeletal muscle regeneration

0098641:cadherin binding involved in cell-cell adhesion

0009986:cell surface

0032652:regulation of interleukin-1 production

1900087:positive regulation of G1/S transition of mitotic cell cycle

0005543:phospholipid binding

0007187:G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

0031313:extrinsic component of endosome membrane

1990814:DNA/DNA annealing activity

0032355:response to estradiol

0031966:mitochondrial membrane

0042493:response to drug

0070459:prolactin secretion

0005102:signaling receptor binding

0003697:single-stranded DNA binding

0031532:actin cytoskeleton reorganization

0042383:sarcolemma

0048306:calcium-dependent protein binding

0050727:regulation of inflammatory response

0001533:cornified envelope

0036121:double-stranded DNA helicase activity

0033031:positive regulation of neutrophil apoptotic process

0070062:extracellular exosome

0070301:cellular response to hydrogen peroxide

0005925:focal adhesion

0002250:adaptive immune response

0045920:negative regulation of exocytosis

0030073:insulin secretion

0030659:cytoplasmic vesicle membrane

0005886:plasma membrane

1900138:negative regulation of phospholipase A2 activity

0031232:extrinsic component of external side of plasma membrane

0031982:vesicle

0032743:positive regulation of interleukin-2 production

0032991:protein-containing complex

0007165:signal transduction

0005654:nucleoplasm

0097350:neutrophil clearance

0042063:gliogenesis

0019221:cytokine-mediated signaling pathway

0016323:basolateral plasma membrane

0007166:cell surface receptor signaling pathway

0031514:motile cilium

0090050:positive regulation of cell migration involved in sprouting angiogenesis

0002685:regulation of leukocyte migration

PDB 5VFW ; 1BO9 ; 1QLS ; 1AIN
Drugbank DB14541 ; DB00591 ; DB14669 ; DB14542 ; DB14538 ; DB14543 ; DB14539 ; DB14631 ; DB00288 ; DB14649 ; DB14540 ; DB00741 ; DB01013 ; DB14544 ; DB01222 ; DB00959 ; DB01234
KEGG hsa:301

Related Compounds  (Total: 1)

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C0456
Name: Tretinoin


Related Herbs  (Total: 2)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0847 Zi He Che紫河车 Human placentaHomo sapiens