HIT-result

Type	Detail
Target ID	T40ENL
Protein Name	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
Uniprot ID	Q9NQ66
Protein Name Alias	EC 3.1.4.11; PLC-154; Phosphoinositide phospholipase C-beta-1; Phospholipase C-I; PLC-I; Phospholipase C-beta-1; PLC-beta-1
Gene ID	23236
Gene Symbol	PLCB1
Gene Alias	KIAA0581
TTD	T26846: Research target
Pfam	PF06631 ; PF08703 ; PF09279 ; PF00388 ; PF00387 ; PF17787
GO	0070062:extracellular exosome 0032991:protein-containing complex 0007223:Wnt signaling pathway, calcium modulating pathway 0098982:GABA-ergic synapse 0016042:lipid catabolic process 2000344:positive regulation of acrosome reaction 0007186:G protein-coupled receptor signaling pathway 0048009:insulin-like growth factor receptor signaling pathway 0007213:G protein-coupled acetylcholine receptor signaling pathway 0007215:glutamate receptor signaling pathway 0060466:activation of meiosis involved in egg activation 0070498:interleukin-1-mediated signaling pathway 0005096:GTPase activator activity 0005829:cytosol 0045444:fat cell differentiation 2000438:negative regulation of monocyte extravasation 0040019:positive regulation of embryonic development 0042802:identical protein binding 0098794:postsynapse 0005516:calmodulin binding 0043647:inositol phosphate metabolic process 1900087:positive regulation of G1/S transition of mitotic cell cycle 0035722:interleukin-12-mediated signaling pathway 0031965:nuclear membrane 0098978:glutamatergic synapse 0019899:enzyme binding 0046330:positive regulation of JNK cascade 0035723:interleukin-15-mediated signaling pathway 0005737:cytoplasm 0045893:positive regulation of transcription, DNA-templated 0080154:regulation of fertilization 0048639:positive regulation of developmental growth 0000785:chromatin 0021987:cerebral cortex development 0007613:memory 0016607:nuclear speck 0008277:regulation of G protein-coupled receptor signaling pathway 0048015:phosphatidylinositol-mediated signaling 0005634:nucleus 0000086:G2/M transition of mitotic cell cycle 0005509:calcium ion binding 0004435:phosphatidylinositol phospholipase C activity 0045892:negative regulation of transcription, DNA-templated 0046488:phosphatidylinositol metabolic process 0005521:lamin binding 1903140:regulation of establishment of endothelial barrier 0045663:positive regulation of myoblast differentiation 0099170:postsynaptic modulation of chemical synaptic transmission 0099178:regulation of retrograde trans-synaptic signaling by endocanabinoid 0007165:signal transduction 0005546:phosphatidylinositol-4,5-bisphosphate binding 0032735:positive regulation of interleukin-12 production 2000560:positive regulation of CD24 production
PDB	NA
Drugbank	NA
KEGG	hsa:23236

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Name: Colchicine

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0560	Cao Bei Mu	草贝母	Indian iphigenia	Iphigenia indica
H0132	Li Lu	藜芦	Black falsehellebore	Veratrum nigrum