HIT-result

Type	Detail
Target ID	T41CZ3
Protein Name	Phospholipid scramblase 1
Uniprot ID	O15162
Protein Name Alias	PL scramblase 1; Ca(2+)-dependent phospholipid scramblase 1; Erythrocyte phospholipid scramblase; Mg(2+)-dependent nuclease; EC 3.1.-.-; MmTRA1b
Gene ID	5359
Gene Symbol	PLSCR1
Gene Alias	NA
TTD	NA
Pfam	PF03803
GO	0030168:platelet activation 0070062:extracellular exosome 0050765:negative regulation of phagocytosis 0004518:nuclease activity 0006953:acute-phase response 0051607:defense response to virus 0005730:nucleolus 0016020:membrane 0060368:regulation of Fc receptor mediated stimulatory signaling pathway 1905820:positive regulation of chromosome separation 0005829:cytosol 0001618:virus receptor activity 0045089:positive regulation of innate immune response 0035456:response to interferon-beta 0006915:apoptotic process 0005794:Golgi apparatus 0001228:DNA-binding transcription activator activity, RNA polymerase II-specific 0005886:plasma membrane 0000287:magnesium ion binding 0010288:response to lead ion 0017121:plasma membrane phospholipid scrambling 0005654:nucleoplasm 0019899:enzyme binding 0005887:integral component of plasma membrane 0005737:cytoplasm 0003677:DNA binding 0048471:perinuclear region of cytoplasm 0008270:zinc ion binding 0017124:SH3 domain binding 0033003:regulation of mast cell activation 0032791:lead ion binding 0006659:phosphatidylserine biosynthetic process 0045944:positive regulation of transcription by RNA polymerase II 0005634:nucleus 0070782:phosphatidylserine exposure on apoptotic cell surface 0045121:membrane raft 0005509:calcium ion binding 2000373:positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity 0010628:positive regulation of gene expression 0005154:epidermal growth factor receptor binding 0042609:CD4 receptor binding 0045071:negative regulation of viral genome replication 0045340:mercury ion binding 0062023:collagen-containing extracellular matrix 0017128:phospholipid scramblase activity
PDB	1Y2A
Drugbank	NA
KEGG	hsa:5359

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Name: rottlerin

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0139	Lian Qiao	连翘	Weeping forsythia	Forsythia suspensa
H1251	Huang Qin	黄芩	Root of Baikal skullcaap	Scutellaria baicalensis