HIT-result

Type	Detail
Target ID	T43TK1
Protein Name	Protein LYRIC
Uniprot ID	Q86UE4
Protein Name Alias	3D3/LYRIC; Astrocyte elevated gene-1 protein; AEG-1; Lysine-rich CEACAM1 co-isolated protein; Metadherin; Metastasis adhesion protein
Gene ID	92140
Gene Symbol	MTDH
Gene Alias	AEG1; LYRIC
TTD	T52547: Research target
Pfam	PF15686
GO	0005634:nucleus 0005789:endoplasmic reticulum membrane 0003713:transcription coactivator activity 0016324:apical plasma membrane 0070830:bicellular tight junction assembly 0051897:positive regulation of protein kinase B signaling 0051092:positive regulation of NF-kappaB transcription factor activity 0005737:cytoplasm 0046581:intercellular canaliculus 0001085:RNA polymerase II transcription factor binding 0003725:double-stranded RNA binding 0051059:NF-kappaB binding 0005783:endoplasmic reticulum 0048471:perinuclear region of cytoplasm 0001650:fibrillar center 0016021:integral component of membrane 0031965:nuclear membrane 0003723:RNA binding 0043123:positive regulation of I-kappaB kinase/NF-kappaB signaling 0016604:nuclear body 0010508:positive regulation of autophagy 0045766:positive regulation of angiogenesis 0000122:negative regulation of transcription by RNA polymerase II 0006357:regulation of transcription by RNA polymerase II 0005923:bicellular tight junction 0003712:transcription coregulator activity 0031663:lipopolysaccharide-mediated signaling pathway 0043066:negative regulation of apoptotic process
PDB	4QMG
Drugbank	NA
KEGG	hsa:92140

Target Description

Related Compounds (Total: 1)

Related Herbs (Total: 1)