HIT-result

Type	Detail
Target ID	T43VO5
Protein Name	Long-chain-fatty-acid--CoA ligase 1
Uniprot ID	P33121
Protein Name Alias	EC 6.2.1.3; Acyl-CoA synthetase 1; ACS1; Arachidonate--CoA ligase; EC 6.2.1.15; Long-chain acyl-CoA synthetase 1; LACS 1; Long-chain acyl-CoA synthetase 2; LACS 2; Long-chain fatty acid-CoA ligase 2; Palmitoyl-CoA ligase 1; Palmitoyl-CoA ligase 2; Phytanate--CoA ligase; EC 6.2.1.24
Gene ID	2180
Gene Symbol	ACSL1
Gene Alias	FACL1; FACL2; LACS; LACS1; LACS2
TTD	NA
Pfam	PF00501 ; PF13193
GO	0010747:positive regulation of long-chain fatty acid import across plasma membrane 0005789:endoplasmic reticulum membrane 0016021:integral component of membrane 0005524:ATP binding 0120162:positive regulation of cold-induced thermogenesis 0042493:response to drug 0005778:peroxisomal membrane 0000038:very long-chain fatty acid metabolic process 0042178:xenobiotic catabolic process 0016020:membrane 0044539:long-chain fatty acid import into cell 0071902:positive regulation of protein serine/threonine kinase activity 0007584:response to nutrient 0005783:endoplasmic reticulum 0035338:long-chain fatty-acyl-CoA biosynthetic process 0043651:linoleic acid metabolic process 0050197:phytanate-CoA ligase activity 0036109:alpha-linolenic acid metabolic process 0005886:plasma membrane 0034201:response to oleic acid 0015908:fatty acid transport 0019432:triglyceride biosynthetic process 0014070:response to organic cyclic compound 0090434:oleoyl-CoA ligase activity 0001676:long-chain fatty acid metabolic process 0005739:mitochondrion 0005741:mitochondrial outer membrane 0004467:long-chain fatty acid-CoA ligase activity 0019222:regulation of metabolic process 0070251:pristanate-CoA ligase activity 0008610:lipid biosynthetic process 0047676:arachidonate-CoA ligase activity 0033211:adiponectin-activated signaling pathway
PDB	NA
Drugbank	DB00131 ; DB00171
KEGG	hsa:2180

Target Description

Related Compounds (Total: 1)

Related Herbs (Total: 0)