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Target Description
Type
Detail
Target ID
T45JVK
Protein Name
Nuclear receptor subfamily 5 group A member 2
Uniprot ID
O00482
Protein Name Alias
Alpha-1-fetoprotein transcription factor; B1-binding factor; hB1F; CYP7A promoter-binding factor; Hepatocytic transcription factor; Liver receptor homolog 1; LRH-1
Gene ID
2494
Gene Symbol
NR5A2
Gene Alias
B1F; CPF; FTF
TTD
T75136: Research target
Pfam
PF00105
;
PF00104
GO
0003677:DNA binding
0005634:nucleus
0043565:sequence-specific DNA binding
0045070:positive regulation of viral genome replication
0009888:tissue development
0006355:regulation of transcription, DNA-templated
0042127:regulation of cell population proliferation
0042592:homeostatic process
0003682:chromatin binding
0090575:RNA polymerase II transcription regulator complex
0005543:phospholipid binding
0005737:cytoplasm
0009755:hormone-mediated signaling pathway
0001228:DNA-binding transcription activator activity, RNA polymerase II-specific
0000785:chromatin
0000976:transcription regulatory region sequence-specific DNA binding
0030855:epithelial cell differentiation
0042632:cholesterol homeostasis
0097720:calcineurin-mediated signaling
0000981:DNA-binding transcription factor activity, RNA polymerase II-specific
0009792:embryo development ending in birth or egg hatching
0045893:positive regulation of transcription, DNA-templated
0008270:zinc ion binding
0003700:DNA-binding transcription factor activity
0008206:bile acid metabolic process
0006357:regulation of transcription by RNA polymerase II
0006367:transcription initiation from RNA polymerase II promoter
0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding
0005654:nucleoplasm
1990837:sequence-specific double-stranded DNA binding
0061113:pancreas morphogenesis
1990830:cellular response to leukemia inhibitory factor
0045944:positive regulation of transcription by RNA polymerase II
0004879:nuclear receptor activity
PDB
1YOK
;
6OQX
;
4PLD
;
5UNJ
;
4DOS
;
5L0M
;
4IS8
;
5SYZ
;
1YUC
;
4ONI
;
6VIF
;
4DOR
;
5L11
;
6VC2
;
1ZDU
;
2A66
;
4RWV
;
6OQY
;
3PLZ
;
4PLE
;
3TX7
;
6OR1
Drugbank
NA
KEGG
hsa:2494
Related Compounds (Total: 1)
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C1228
Name: Chenodiol
Related Herbs (Total: 2)
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Herb id
Chinese Pin Yin
Chinese Character
English Name
Latin Name
H0847
Zi He Che
紫河车
Human placenta
Homo sapiens
H0360
Ren Zhong Bai
人中白
Human urine sediment
Homo sapiens