Target Description

Type Detail
Target ID T45JVK
Protein Name Nuclear receptor subfamily 5 group A member 2
Uniprot ID O00482
Protein Name Alias Alpha-1-fetoprotein transcription factor;  B1-binding factor;  hB1F;  CYP7A promoter-binding factor;  Hepatocytic transcription factor;  Liver receptor homolog 1;  LRH-1
Gene ID 2494
Gene Symbol NR5A2
Gene Alias B1F;  CPF;  FTF
TTD T75136: Research target
Pfam PF00105 ; PF00104
GO
0003677:DNA binding

0005634:nucleus

0043565:sequence-specific DNA binding

0045070:positive regulation of viral genome replication

0009888:tissue development

0006355:regulation of transcription, DNA-templated

0042127:regulation of cell population proliferation

0042592:homeostatic process

0003682:chromatin binding

0090575:RNA polymerase II transcription regulator complex

0005543:phospholipid binding

0005737:cytoplasm

0009755:hormone-mediated signaling pathway

0001228:DNA-binding transcription activator activity, RNA polymerase II-specific

0000785:chromatin

0000976:transcription regulatory region sequence-specific DNA binding

0030855:epithelial cell differentiation

0042632:cholesterol homeostasis

0097720:calcineurin-mediated signaling

0000981:DNA-binding transcription factor activity, RNA polymerase II-specific

0009792:embryo development ending in birth or egg hatching

0045893:positive regulation of transcription, DNA-templated

0008270:zinc ion binding

0003700:DNA-binding transcription factor activity

0008206:bile acid metabolic process

0006357:regulation of transcription by RNA polymerase II

0006367:transcription initiation from RNA polymerase II promoter

0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding

0005654:nucleoplasm

1990837:sequence-specific double-stranded DNA binding

0061113:pancreas morphogenesis

1990830:cellular response to leukemia inhibitory factor

0045944:positive regulation of transcription by RNA polymerase II

0004879:nuclear receptor activity

PDB 1YOK ; 6OQX ; 4PLD ; 5UNJ ; 4DOS ; 5L0M ; 4IS8 ; 5SYZ ; 1YUC ; 4ONI ; 6VIF ; 4DOR ; 5L11 ; 6VC2 ; 1ZDU ; 2A66 ; 4RWV ; 6OQY ; 3PLZ ; 4PLE ; 3TX7 ; 6OR1
Drugbank NA
KEGG hsa:2494

Related Compounds  (Total: 1)

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C1228
Name: Chenodiol


Related Herbs  (Total: 2)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens