Target Description

Type Detail
Target ID T49M88
Protein Name Diacylglycerol O-acyltransferase 2
Uniprot ID Q96PD7
Protein Name Alias EC 2.3.1.20;  Acyl-CoA retinol O-fatty-acyltransferase;  ARAT;  Retinol O-fatty-acyltransferase;  EC 2.3.1.76;  Diglyceride acyltransferase 2
Gene ID 84649
Gene Symbol DGAT2
Gene Alias NA
TTD T95558: Successful target
Pfam PF03982
GO
0046322:negative regulation of fatty acid oxidation

0003846:2-acylglycerol O-acyltransferase activity

0005789:endoplasmic reticulum membrane

0016021:integral component of membrane

0005811:lipid droplet

0042632:cholesterol homeostasis

0050252:retinol O-fatty-acyltransferase activity

0010867:positive regulation of triglyceride biosynthetic process

0046339:diacylglycerol metabolic process

0050746:regulation of lipoprotein metabolic process

0005829:cytosol

0006071:glycerol metabolic process

0045722:positive regulation of gluconeogenesis

0034383:low-density lipoprotein particle clearance

0008374:O-acyltransferase activity

0006629:lipid metabolic process

0006651:diacylglycerol biosynthetic process

0035356:cellular triglyceride homeostasis

0019432:triglyceride biosynthetic process

0004144:diacylglycerol O-acyltransferase activity

0097006:regulation of plasma lipoprotein particle levels

0048471:perinuclear region of cytoplasm

0005783:endoplasmic reticulum

0030176:integral component of endoplasmic reticulum membrane

0005739:mitochondrion

0071400:cellular response to oleic acid

0036155:acylglycerol acyl-chain remodeling

0042803:protein homodimerization activity

0055089:fatty acid homeostasis

0035336:long-chain fatty-acyl-CoA metabolic process

0006640:monoacylglycerol biosynthetic process

0060613:fat pad development

0038183:bile acid signaling pathway

1990578:perinuclear endoplasmic reticulum membrane

0090181:regulation of cholesterol metabolic process

0019915:lipid storage

0043231:intracellular membrane-bounded organelle

PDB NA
Drugbank DB08949 ; DB13961 ; DB09568
KEGG hsa:84649

Related Compounds  (Total: 1)

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C0965
Name: taxifolin


Related Herbs  (Total: 0)

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