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Target Description
Type
Detail
Target ID
T49M88
Protein Name
Diacylglycerol O-acyltransferase 2
Uniprot ID
Q96PD7
Protein Name Alias
EC 2.3.1.20; Acyl-CoA retinol O-fatty-acyltransferase; ARAT; Retinol O-fatty-acyltransferase; EC 2.3.1.76; Diglyceride acyltransferase 2
Gene ID
84649
Gene Symbol
DGAT2
Gene Alias
NA
TTD
T95558: Successful target
Pfam
PF03982
GO
0046322:negative regulation of fatty acid oxidation
0003846:2-acylglycerol O-acyltransferase activity
0005789:endoplasmic reticulum membrane
0016021:integral component of membrane
0005811:lipid droplet
0042632:cholesterol homeostasis
0050252:retinol O-fatty-acyltransferase activity
0010867:positive regulation of triglyceride biosynthetic process
0046339:diacylglycerol metabolic process
0050746:regulation of lipoprotein metabolic process
0005829:cytosol
0006071:glycerol metabolic process
0045722:positive regulation of gluconeogenesis
0034383:low-density lipoprotein particle clearance
0008374:O-acyltransferase activity
0006629:lipid metabolic process
0006651:diacylglycerol biosynthetic process
0035356:cellular triglyceride homeostasis
0019432:triglyceride biosynthetic process
0004144:diacylglycerol O-acyltransferase activity
0097006:regulation of plasma lipoprotein particle levels
0048471:perinuclear region of cytoplasm
0005783:endoplasmic reticulum
0030176:integral component of endoplasmic reticulum membrane
0005739:mitochondrion
0071400:cellular response to oleic acid
0036155:acylglycerol acyl-chain remodeling
0042803:protein homodimerization activity
0055089:fatty acid homeostasis
0035336:long-chain fatty-acyl-CoA metabolic process
0006640:monoacylglycerol biosynthetic process
0060613:fat pad development
0038183:bile acid signaling pathway
1990578:perinuclear endoplasmic reticulum membrane
0090181:regulation of cholesterol metabolic process
0019915:lipid storage
0043231:intracellular membrane-bounded organelle
PDB
NA
Drugbank
DB08949
;
DB13961
;
DB09568
KEGG
hsa:84649
Related Compounds (Total: 1)
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C0965
Name: taxifolin
Related Herbs (Total: 0)
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