HIT-result

Type	Detail
Target ID	T50C67
Protein Name	Stimulator of interferon genes protein
Uniprot ID	Q86WV6
Protein Name Alias	hSTING; Endoplasmic reticulum interferon stimulator; ERIS; Mediator of IRF3 activation; hMITA; Transmembrane protein 173
Gene ID	340061
Gene Symbol	STING1
Gene Alias	ERIS; MITA; TMEM173
TTD	T99338: Clinical Trial target
Pfam	PF15009
GO	0008134:transcription factor binding 0042802:identical protein binding 0030667:secretory granule membrane 1990701:integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane 0071360:cellular response to exogenous dsRNA 0051607:defense response to virus 0061507:cyclic-GMP-AMP binding 0005789:endoplasmic reticulum membrane 0005829:cytosol 0035458:cellular response to interferon-beta 0031625:ubiquitin protein ligase binding 0051259:protein complex oligomerization 0030176:integral component of endoplasmic reticulum membrane 0002218:activation of innate immune response 0071407:cellular response to organic cyclic compound 0030659:cytoplasmic vesicle membrane 0019901:protein kinase binding 0005776:autophagosome 0005886:plasma membrane 0048471:perinuclear region of cytoplasm 0032092:positive regulation of protein binding 0005741:mitochondrial outer membrane 0032479:regulation of type I interferon production 0043312:neutrophil degranulation 0032728:positive regulation of interferon-beta production 0002230:positive regulation of defense response to virus by host 0032481:positive regulation of type I interferon production 0061709:reticulophagy 0005794:Golgi apparatus 0051091:positive regulation of DNA-binding transcription factor activity 0042803:protein homodimerization activity 0016032:viral process 0005777:peroxisome 0000045:autophagosome assembly 0050727:regulation of inflammatory response 0005654:nucleoplasm 0016239:positive regulation of macroautophagy 0000421:autophagosome membrane 0035438:cyclic-di-GMP binding 0045944:positive regulation of transcription by RNA polymerase II 0005768:endosome 0045087:innate immune response
PDB	6RM0 ; 4QXR ; 6NT5 ; 6DXL ; 6UKM ; 4EMT ; 4F9G ; 6S86 ; 6O8C ; 6DXG ; 6UKW ; 6UKZ ; 5JEJ ; 4F9E ; 6S27 ; 6UKV ; 6O8B ; 6UKX ; 6XNP ; 6MXE ; 4F5E ; 6UKU ; 6CY7 ; 6UL0 ; 6MX3 ; 4EF5 ; 4KSY ; 6MX0 ; 4EMU ; 6CFF ; 4LOH ; 6UKY ; 4QXQ ; 4QXO ; 4EF4 ; 4F5D ; 5BQX ; 4QXP ; 6S26 ; 4F5Y ; 4LOI ; 4F5W ; 6DNK
Drugbank	NA
KEGG	hsa:340061

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Name: Sulforaphane

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0125	Lai Fu	莱菔	Garden radish	Raphanus sativus
H0466	Cai Fu Zi	菜菔子	Semen raphani	Raphanus sativus
H0960	Dang Shen Qing Gao	党参清膏	Root of hairy asiabell	Codonopsis pilosula
H0958	Dang Shen	党参	Pilose asiabell	Codonopsis pilosula
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0126	Lai Fu Zi	莱菔子	Garden radish seed	Raphanus sativus