HIT-result

Type	Detail
Target ID	T50FPV
Protein Name	Interleukin-7 receptor subunit alpha
Uniprot ID	P16871
Protein Name Alias	IL-7 receptor subunit alpha; IL-7R subunit alpha; IL-7R-alpha; IL-7RA; CDw127; CD antigen CD127
Gene ID	3575
Gene Symbol	IL7R
Gene Alias	NA
TTD	T85025: Clinical Trial target
Pfam	PF18447 ; PF00041
GO	0000902:cell morphogenesis 0042100:B cell proliferation 0038111:interleukin-7-mediated signaling pathway 0005829:cytosol 0070233:negative regulation of T cell apoptotic process 0008284:positive regulation of cell population proliferation 0006955:immune response 0061024:membrane organization 1904894:positive regulation of receptor signaling pathway via STAT 0001915:negative regulation of T cell mediated cytotoxicity 0048535:lymph node development 0033089:positive regulation of T cell differentiation in thymus 0030217:T cell differentiation 0000018:regulation of DNA recombination 0004917:interleukin-7 receptor activity 0010628:positive regulation of gene expression 0005886:plasma membrane 0016021:integral component of membrane 0003823:antigen binding 0030669:clathrin-coated endocytic vesicle membrane 0005576:extracellular region 0050830:defense response to Gram-positive bacterium 0048872:homeostasis of number of cells 0007165:signal transduction 0005654:nucleoplasm 0008361:regulation of cell size 0004896:cytokine receptor activity 0007166:cell surface receptor signaling pathway 0009897:external side of plasma membrane
PDB	5J11 ; 6P50 ; 3DI3 ; 3UP1 ; 3DI2 ; 6P67
Drugbank	NA
KEGG	hsa:3575

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Name: Apicidin

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0794	Zhe Bei Mu	浙贝母	Thunberg fritillary	Fritillaria verticillata var. thunbergii