Compound Description

ID:   C0803 Common name:   Apicidin
IUPAC:  (3S,6S,9S,12R)-3-[(2S)-butan-2-yl]-6-[(1-methoxyindol-3-yl)methyl]-9-(6-oxooctyl)-1,4,7,10-tetrazabicyclo[10.4.0]hexadecane-2,5,8,11-tetrone CAS:  CAS:183506-66-3
Chembl ID:   CHEMBL430060 Pubchem ID:   CID:6918328
Formula:  C34H49N5O6 TCM-ID:  TCMC5174
Smiles:  CCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CCCCN2C(=O)[C@@H](NC(=O)[C@@H](NC1=O)Cc1cn(c2c1cccc2)OC)[C@H](CC)C
Alias:

Cyclo(8-oxo-L-2-aminodecanoyl-1-methoxy-L-tryptophyl-L-isoleucyl-D-2-piperidinecarbonyl);

Apicidin;

Apicidin Ia;

OSI 2040
Structure:

Related Targets  (Total: 4)

Target idProtein NameGene SymbolUniprot IDTarget LevelNo.of Literature Evidence
T68DAN Histone deacetylase 9HDAC9 Q9UKV0
A 3 Reference(s)
T68M1D Histone deacetylase 2HDAC2 Q92769
A 1 Reference(s)
T38AWT Histone deacetylase 3HDAC3 O15379
A 2 Reference(s)
T50FPV Interleukin-7 receptor subunit alphaIL7R P16871
C 1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Related Herbs  (Total: 1)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0794 Zhe Bei Mu浙贝母 Thunberg fritillaryFritillaria verticillata var. thunbergii