HIT-result

Type	Detail
Target ID	T50HKY
Protein Name	cAMP-dependent protein kinase type I-alpha regulatory subunit
Uniprot ID	P10644
Protein Name Alias	Tissue-specific extinguisher 1; TSE1
Gene ID	5573
Gene Symbol	PRKAR1A
Gene Alias	PKR1; PRKAR1; TSE1
TTD	T08813: Research target
Pfam	PF00027 ; PF02197
GO	0002862:negative regulation of inflammatory response to antigenic stimulus 0031588:nucleotide-activated protein kinase complex 0060038:cardiac muscle cell proliferation 0035556:intracellular signal transduction 0004862:cAMP-dependent protein kinase inhibitor activity 0016020:membrane 0098978:glutamatergic synapse 0003091:renal water homeostasis 0005813:centrosome 0044853:plasma membrane raft 0031594:neuromuscular junction 0045835:negative regulation of meiotic nuclear division 0006357:regulation of transcription by RNA polymerase II 0008603:cAMP-dependent protein kinase regulator activity 0001707:mesoderm formation 0043949:regulation of cAMP-mediated signaling 0031625:ubiquitin protein ligase binding 0007268:chemical synaptic transmission 0032991:protein-containing complex 0045214:sarcomere organization 0010738:regulation of protein kinase A signaling 0097224:sperm connecting piece 0007143:female meiotic nuclear division 0005737:cytoplasm 2000480:negative regulation of cAMP-dependent protein kinase activity 0034199:activation of protein kinase A activity 0046007:negative regulation of activated T cell proliferation 0071377:cellular response to glucagon stimulus 0030552:cAMP binding 0005952:cAMP-dependent protein kinase complex 0005829:cytosol 0097546:ciliary base 0005771:multivesicular body 0034236:protein kinase A catalytic subunit binding 0007596:blood coagulation 0019904:protein domain specific binding
PDB	5KJZ ; 5KJX ; 5KJY
Drugbank	DB02527 ; DB01790 ; DB02315 ; DB05798
KEGG	hsa:5573

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Name: Paclitaxel

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0515	Suan Shi Liu	酸石榴	Pomegranate	Punica granatum
H0462	Shi Liu	石榴	Pomegranate fruit	Punica granatum
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0463	Shi Liu Pi	石榴皮	Pomegranate peel	Punica granatum
H0464	Shi Liu Zi	石榴子	NA	Punica granatum