HIT-result

Type	Detail
Target ID	T50OPC
Protein Name	Indian hedgehog protein
Uniprot ID	Q14623
Protein Name Alias	IHH; HHG-2
Gene ID	3549
Gene Symbol	IHH
Gene Alias	NA
TTD	NA
Pfam	PF01079 ; PF01085
GO	0035264:multicellular organism growth 0048666:neuron development 0046639:negative regulation of alpha-beta T cell differentiation 0033088:negative regulation of immature T cell proliferation in thymus 0048596:embryonic camera-type eye morphogenesis 0033085:negative regulation of T cell differentiation in thymus 0048469:cell maturation 0006029:proteoglycan metabolic process 0009612:response to mechanical stimulus 0010468:regulation of gene expression 0001947:heart looping 0003382:epithelial cell morphogenesis 0061053:somite development 0045453:bone resorption 0042733:embryonic digit morphogenesis 0045880:positive regulation of smoothened signaling pathway 0016539:intein-mediated protein splicing 0048745:smooth muscle tissue development 0060220:camera-type eye photoreceptor cell fate commitment 0050679:positive regulation of epithelial cell proliferation 0051216:cartilage development 0005509:calcium ion binding 0033089:positive regulation of T cell differentiation in thymus 0005615:extracellular space 0007224:smoothened signaling pathway 0048074:negative regulation of eye pigmentation 0060323:head morphogenesis 0031016:pancreas development 0002053:positive regulation of mesenchymal cell proliferation 0005886:plasma membrane 0046638:positive regulation of alpha-beta T cell differentiation 0009880:embryonic pattern specification 0090136:epithelial cell-cell adhesion 0032355:response to estradiol 0001701:in utero embryonic development 0003413:chondrocyte differentiation involved in endochondral bone morphogenesis 0007267:cell-cell signaling 0001569:branching involved in blood vessel morphogenesis 0001649:osteoblast differentiation 0030704:vitelline membrane formation 0032967:positive regulation of collagen biosynthetic process 0097421:liver regeneration 0072498:embryonic skeletal joint development 0003406:retinal pigment epithelium development 0060135:maternal process involved in female pregnancy 0008233:peptidase activity 0048557:embryonic digestive tract morphogenesis 0035988:chondrocyte proliferation 0016540:protein autoprocessing 0001501:skeletal system development 0031012:extracellular matrix 0001708:cell fate specification 0045944:positive regulation of transcription by RNA polymerase II 0040008:regulation of growth 0043066:negative regulation of apoptotic process 0005113:patched binding
PDB	3K7J ; 3N1O ; 3N1P ; 3N1M ; 3K7I ; 3N1F ; 3K7G ; 3K7H
Drugbank	NA
KEGG	hsa:3549

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Name: Cyclopamine

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0214	Bei He Huan	北合欢	Albizia	Albizia julibrissin