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Target Description
Type
Detail
Target ID
T51RUY
Protein Name
Cell division cycle 7-related protein kinase
Uniprot ID
O00311
Protein Name Alias
CDC7-related kinase; HsCdc7; huCdc7; EC 2.7.11.1
Gene ID
8317
Gene Symbol
CDC7
Gene Alias
CDC7L1
TTD
T81358: Clinical Trial target
Pfam
PF00069
GO
0005634:nucleus
0004672:protein kinase activity
0106310:protein serine kinase activity
0004674:protein serine/threonine kinase activity
0106311:protein threonine kinase activity
0045171:intercellular bridge
0008284:positive regulation of cell population proliferation
0016301:kinase activity
0018105:peptidyl-serine phosphorylation
0006270:DNA replication initiation
0005524:ATP binding
0000727:double-strand break repair via break-induced replication
0006260:DNA replication
0072686:mitotic spindle
0044770:cell cycle phase transition
0005737:cytoplasm
0051301:cell division
0005654:nucleoplasm
0046872:metal ion binding
0000082:G1/S transition of mitotic cell cycle
0010971:positive regulation of G2/M transition of mitotic cell cycle
0010571:positive regulation of nuclear cell cycle DNA replication
0070317:negative regulation of G0 to G1 transition
PDB
5UWQ
;
4F9C
;
4F9B
;
6YA7
;
4F9A
;
4F99
;
6YA6
;
5UWR
;
6YA8
Drugbank
NA
KEGG
hsa:8317
Related Compounds (Total: 1)
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C0913
Name: Ap
Related Herbs (Total: 2)
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Herb id
Chinese Pin Yin
Chinese Character
English Name
Latin Name
H0847
Zi He Che
紫河车
Human placenta
Homo sapiens
H0360
Ren Zhong Bai
人中白
Human urine sediment
Homo sapiens