Target Description

Type Detail
Target ID T51RUY
Protein Name Cell division cycle 7-related protein kinase
Uniprot ID O00311
Protein Name Alias CDC7-related kinase;  HsCdc7;  huCdc7;  EC
Gene ID 8317
Gene Symbol CDC7
Gene Alias CDC7L1
TTD T81358: Clinical Trial target
Pfam PF00069

0004672:protein kinase activity

0106310:protein serine kinase activity

0004674:protein serine/threonine kinase activity

0106311:protein threonine kinase activity

0045171:intercellular bridge

0008284:positive regulation of cell population proliferation

0016301:kinase activity

0018105:peptidyl-serine phosphorylation

0006270:DNA replication initiation

0005524:ATP binding

0000727:double-strand break repair via break-induced replication

0006260:DNA replication

0072686:mitotic spindle

0044770:cell cycle phase transition


0051301:cell division


0046872:metal ion binding

0000082:G1/S transition of mitotic cell cycle

0010971:positive regulation of G2/M transition of mitotic cell cycle

0010571:positive regulation of nuclear cell cycle DNA replication

0070317:negative regulation of G0 to G1 transition

PDB 5UWQ ; 4F9C ; 4F9B ; 6YA7 ; 4F9A ; 4F99 ; 6YA6 ; 5UWR ; 6YA8
Drugbank NA
KEGG hsa:8317

Related Compounds  (Total: 1)

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Name: Ap

Related Herbs  (Total: 2)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0847 Zi He Che紫河车 Human placentaHomo sapiens