HIT-result

Target Description

Type	Detail
Target ID	T52S7S
Protein Name	Neuromedin-K receptor
Uniprot ID	P29371
Protein Name Alias	NKR; NK-3 receptor; NK-3R; Neurokinin B receptor; Tachykinin receptor 3
Gene ID	6870
Gene Symbol	TACR3
Gene Alias	NK3R; TAC3R
TTD	T29683: Clinical Trial target
Pfam	PF00001
GO	0007568:aging 0005634:nucleus 0004995:tachykinin receptor activity 0070474:positive regulation of uterine smooth muscle contraction 0032590:dendrite membrane 0005887:integral component of plasma membrane 0005886:plasma membrane 0032355:response to estradiol 0042538:hyperosmotic salinity response 1902093:positive regulation of flagellated sperm motility 0045777:positive regulation of blood pressure 0060259:regulation of feeding behavior 0097225:sperm midpiece 0005737:cytoplasm 0007186:G protein-coupled receptor signaling pathway 0007217:tachykinin receptor signaling pathway 0043278:response to morphine 0042053:regulation of dopamine metabolic process 0032809:neuronal cell body membrane 0010460:positive regulation of heart rate 0042220:response to cocaine
PDB	NA
Drugbank	DB11692 ; DB04872 ; DB06429
KEGG	hsa:6870

Type

Detail

Target ID

T52S7S

Protein Name

Neuromedin-K receptor

Uniprot ID

P29371

Protein Name Alias

NKR; NK-3 receptor; NK-3R; Neurokinin B receptor; Tachykinin receptor 3

Gene ID

6870

Gene Symbol

TACR3

Gene Alias

NK3R; TAC3R

TTD

T29683: Clinical Trial target

Pfam

PF00001

0007568:aging

0005634:nucleus

0004995:tachykinin receptor activity

0070474:positive regulation of uterine smooth muscle contraction

0032590:dendrite membrane

0005887:integral component of plasma membrane

0005886:plasma membrane

0032355:response to estradiol

0042538:hyperosmotic salinity response

1902093:positive regulation of flagellated sperm motility

0045777:positive regulation of blood pressure

0060259:regulation of feeding behavior

0097225:sperm midpiece

0005737:cytoplasm

0007186:G protein-coupled receptor signaling pathway

0007217:tachykinin receptor signaling pathway

0043278:response to morphine

0042053:regulation of dopamine metabolic process

0032809:neuronal cell body membrane

0010460:positive regulation of heart rate

0042220:response to cocaine

PDB

Drugbank

DB11692 ; DB04872 ; DB06429

KEGG

hsa:6870

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0854	Zi Wei Gen Pi	紫葳根皮	NA	Campsis grandiflora
H0123	La Jiao Liu Jin Gao	辣椒流浸膏	Bush redpepper	Capsicum frutescens
H0242	Bei Sha Shen Liu Jin Gao	北沙参流浸膏	Glehnia littoralis	Glehnia littoralis
H0119	La Jiao	辣椒	Bush redpepper	Capsicum frutescens
H0227	Mang Guo Ye	芒果叶	Mango leaf	Mangifera indica
H0121	La Jiao Jin Chu Ye	辣椒浸出液	Bush redpepper	Capsicum frutescens
H0239	Bei Sha Shen	北沙参	Coastal glehnia	Glehnia littoralis
H0122	La Jiao Jin Gao	辣椒浸膏	Bush redpepper	Capsicum frutescens

Target Description

Related Compounds (Total: 1)

Related Herbs (Total: 8)