HIT-result

Type	Detail
Target ID	T54FKY
Protein Name	Serine/threonine-protein kinase Nek2
Uniprot ID	P51955
Protein Name Alias	EC 2.7.11.1; HSPK 21; Never in mitosis A-related kinase 2; NimA-related protein kinase 2; NimA-like protein kinase 1
Gene ID	4751
Gene Symbol	NEK2
Gene Alias	NEK2A; NLK1
TTD	T49102: Research target
Pfam	PF00069
GO	0005634:nucleus 0051988:regulation of attachment of spindle microtubules to kinetochore 0046777:protein autophosphorylation 0007096:regulation of exit from mitosis 0010389:regulation of G2/M transition of mitotic cell cycle 0004672:protein kinase activity 0106310:protein serine kinase activity 0000070:mitotic sister chromatid segregation 0005829:cytosol 0004674:protein serine/threonine kinase activity 0000794:condensed nuclear chromosome 0106311:protein threonine kinase activity 0097711:ciliary basal body-plasma membrane docking 0051973:positive regulation of telomerase activity 0007088:regulation of mitotic nuclear division 0005813:centrosome 0005874:microtubule 0000922:spindle pole 0005737:cytoplasm 1903126:negative regulation of centriole-centriole cohesion 0051225:spindle assembly 0046602:regulation of mitotic centrosome separation 0005524:ATP binding 0000777:condensed chromosome kinetochore 0030496:midbody 0051299:centrosome separation 0051321:meiotic cell cycle 0043392:negative regulation of DNA binding 0005730:nucleolus 0007059:chromosome segregation 1904355:positive regulation of telomere capping 0032991:protein-containing complex 0000776:kinetochore 0006468:protein phosphorylation 0032212:positive regulation of telomere maintenance via telomerase 0000278:mitotic cell cycle 0090307:mitotic spindle assembly 0051301:cell division 0000086:G2/M transition of mitotic cell cycle 0005654:nucleoplasm 0046872:metal ion binding 0019903:protein phosphatase binding 0001824:blastocyst development
PDB	2JAV ; 4AFE ; 2XK8 ; 6SK9 ; 6SGD ; 2WQO ; 2XNM ; 2XNO ; 2XK3 ; 2XK6 ; 5M53 ; 5M55 ; 5M51 ; 2XKD ; 6SGH ; 2XKE ; 6SGI ; 6SGK ; 5M57 ; 2XNN ; 2W5H ; 2XKF ; 2XK4 ; 6TM5 ; 2W5B ; 2W5A ; 2XKC ; 4A4X ; 2XNP ; 2XK7
Drugbank	DB12010 ; DB07180
KEGG	hsa:4751

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Name: Deguelin

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0683	Xiu Xian Ju	绣线菊	Japanese spiraea	Spiraea japonica
H0669	Xie Bai	薤白	Longstamen onion	Allium macrostemon