Compound Description

ID:   C0003 Common name:   Deguelin
Chembl ID:   CHEMBL393417 Pubchem ID:   CID:107935
Formula:  C23H22O6 TCM-ID:  TCMC1001
Smiles:  COc1cc2c(cc1OC)OC[C@@H]1[C@H]2C(=O)c2c(O1)c1C=CC(Oc1cc2)(C)C


Related Targets  (Total: 13)

Target idProtein NameGene SymbolUniprot IDTarget LevelNo.of Literature Evidence
T88TDZ RAC-alpha serine/threonine-protein kinaseAKT1 P31749
A 4 Reference(s)
T01E7W Aurora kinase BAURKB Q96GD4
A 3 Reference(s)
T13YN2 Bcl-2-like protein 1Bcl2l1 Q64373
B 1 Reference(s)
T06RMZ Nuclear factor NF-kappa-B p105 subunitNFKB1 P19838
B 1 Reference(s)
T96OOK Signal transducer and activator of transcription 3STAT3 P40763
C 1 Reference(s)
T92AMR Hepatocyte growth factor receptorMET P08581
C 1 Reference(s)
T67HAF Signal transducer and activator of transcription 1-alpha/betaSTAT1 P42224
C 1 Reference(s)
T81I6O NucleophosminNPM1 P06748
C 1 Reference(s)
T37PW4 DNA replication licensing factor MCM3MCM3 P25205
C 1 Reference(s)
T93OBS Cell division control protein 45 homologCDC45 O75419
C 1 Reference(s)
T82ALJ Glycogen synthase kinase-3 betaGSK3B P49841
C 1 Reference(s)
T54FKY Serine/threonine-protein kinase Nek2NEK2 P51955
C 1 Reference(s)
T40JZG GPI-anchor transamidasePIGK Q92643
C 1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Related Herbs  (Total: 2)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0683 Xiu Xian Ju绣线菊 Japanese spiraeaSpiraea japonica
H0669 Xie Bai薤白 Longstamen onionAllium macrostemon