HIT-result

Type	Detail
Target ID	T55H1Y
Protein Name	Cytochrome P450 26A1
Uniprot ID	O43174
Protein Name Alias	EC 1.14.13.-; Cytochrome P450 retinoic acid-inactivating 1; Cytochrome P450RAI; hP450RAI; Retinoic acid 4-hydroxylase; Retinoic acid-metabolizing cytochrome
Gene ID	1592
Gene Symbol	CYP26A1
Gene Alias	CYP26; P450RAI1
TTD	T84634: Clinical Trial target
Pfam	PF00067
GO	0001972:retinoic acid binding 0034653:retinoic acid catabolic process 0048387:negative regulation of retinoic acid receptor signaling pathway 0016709:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 0033189:response to vitamin A 0005506:iron ion binding 0004497:monooxygenase activity 0032526:response to retinoic acid 0020037:heme binding 0005789:endoplasmic reticulum membrane 0062182:all-trans retinoic acid 4-hydrolase activity 0006805:xenobiotic metabolic process 0001822:kidney development 0062183:all-trans retinoic acid 18-hydroxylase activity 0019825:oxygen binding 0008401:retinoic acid 4-hydroxylase activity 0042573:retinoic acid metabolic process 0016491:oxidoreductase activity 0006766:vitamin metabolic process 0016125:sterol metabolic process
PDB	NA
Drugbank	DB00162 ; DB13083 ; DB00755
KEGG	hsa:1592

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens

Target Description