Target Description

Type Detail
Target ID T57WWD
Protein Name Eukaryotic translation initiation factor 4 gamma 1
Uniprot ID Q04637
Protein Name Alias eIF-4-gamma 1;  eIF-4G 1;  eIF-4G1;  p220
Gene ID 1981
Gene Symbol EIF4G1
Gene Alias EIF4F;  EIF4G;  EIF4GI
TTD NA
Pfam PF02847 ; PF02020 ; PF02854
GO
0010942:positive regulation of cell death

0006412:translation

0005524:ATP binding

0045666:positive regulation of neuron differentiation

0003729:mRNA binding

0080135:regulation of cellular response to stress

0016020:membrane

0033138:positive regulation of peptidyl-serine phosphorylation

0000184:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

1905606:regulation of presynapse assembly

0005829:cytosol

0002191:cap-dependent translational initiation

1905612:positive regulation of mRNA cap binding

0060964:regulation of gene silencing by miRNA

0042802:identical protein binding

0097009:energy homeostasis

1905537:positive regulation of eukaryotic translation initiation factor 4F complex assembly

1900087:positive regulation of G1/S transition of mitotic cell cycle

0030307:positive regulation of cell growth

0001662:behavioral fear response

0005737:cytoplasm

1905696:regulation of polysome binding

1905618:positive regulation of miRNA mediated inhibition of translation

1901215:negative regulation of neuron death

0005844:polysome

0006413:translational initiation

0032502:developmental process

0003723:RNA binding

0008190:eukaryotic initiation factor 4E binding

0036493:positive regulation of translation in response to endoplasmic reticulum stress

0005634:nucleus

0031669:cellular response to nutrient levels

0016281:eukaryotic translation initiation factor 4F complex

0003743:translation initiation factor activity

0060090:molecular adaptor activity

0034645:cellular macromolecule biosynthetic process

0010494:cytoplasmic stress granule

0010801:negative regulation of peptidyl-threonine phosphorylation

0032270:positive regulation of cellular protein metabolic process

0031369:translation initiation factor binding

0010507:negative regulation of autophagy

0006446:regulation of translational initiation

0016032:viral process

0008135:translation factor activity, RNA binding

0043488:regulation of mRNA stability

PDB 4F02 ; 5T46 ; 2W97 ; 5EIR ; 5EI3 ; 1UG3 ; 4AZA ; 1LJ2 ; 6ZMW ; 5EHC
Drugbank NA
KEGG hsa:1981

Related Compounds  (Total: 1)

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C0590
Name: Α-Elemene,Β-Elemene


Related Herbs  (Total: 2)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0103 Ai Ye艾叶 Argy wormwood leafArtemisia argyi
H0430 She Chuang Zi蛇床子 Common cnidiumCnidium monnieri