HIT-result

Target Description

Type	Detail
Target ID	T59NBL
Protein Name	CD209 antigen
Uniprot ID	Q9NNX6
Protein Name Alias	C-type lectin domain family 4 member L; Dendritic cell-specific ICAM-3-grabbing non-integrin 1; DC-SIGN; DC-SIGN1; CD antigen CD209
Gene ID	30835
Gene Symbol	CD209
Gene Alias	CLEC4L
TTD	T59082: Research target
Pfam	PF00059
GO	0042102:positive regulation of T cell proliferation 0035556:intracellular signal transduction 1903902:positive regulation of viral life cycle 0005537:mannose binding 0002250:adaptive immune response 0042605:peptide antigen binding 0046790:virion binding 0002223:stimulatory C-type lectin receptor signaling pathway 0019079:viral genome replication 0005737:cytoplasm 0019048:modulation by virus of host process 0005886:plasma membrane 0075733:intracellular transport of virus 0016021:integral component of membrane 0046718:viral entry into host cell 0043657:host cell 0046968:peptide antigen transport 0016020:membrane 0030246:carbohydrate binding 0042129:regulation of T cell proliferation 0009986:cell surface 0005576:extracellular region 0007157:heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules 0009988:cell-cell recognition 0007159:leukocyte cell-cell adhesion 0006897:endocytosis 0046872:metal ion binding 0001618:virus receptor activity 0009897:external side of plasma membrane 0019882:antigen processing and presentation 0019062:virion attachment to host cell 0097323:B cell adhesion 0045087:innate immune response
PDB	2B6B ; 2IT5 ; 6GHV ; 1SL5 ; 2XR6 ; 1K9I ; 2IT6 ; 1SL4 ; 2XR5
Drugbank	NA
KEGG	hsa:30835

Type

Detail

Target ID

T59NBL

Protein Name

CD209 antigen

Uniprot ID

Q9NNX6

Protein Name Alias

C-type lectin domain family 4 member L; Dendritic cell-specific ICAM-3-grabbing non-integrin 1; DC-SIGN; DC-SIGN1; CD antigen CD209

Gene ID

30835

Gene Symbol

CD209

Gene Alias

CLEC4L

TTD

T59082: Research target

Pfam

PF00059

0042102:positive regulation of T cell proliferation

0035556:intracellular signal transduction

1903902:positive regulation of viral life cycle

0005537:mannose binding

0002250:adaptive immune response

0042605:peptide antigen binding

0046790:virion binding

0002223:stimulatory C-type lectin receptor signaling pathway

0019079:viral genome replication

0005737:cytoplasm

0019048:modulation by virus of host process

0005886:plasma membrane

0075733:intracellular transport of virus

0016021:integral component of membrane

0046718:viral entry into host cell

0043657:host cell

0046968:peptide antigen transport

0016020:membrane

0030246:carbohydrate binding

0042129:regulation of T cell proliferation

0009986:cell surface

0005576:extracellular region

0007157:heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

0009988:cell-cell recognition

0007159:leukocyte cell-cell adhesion

0006897:endocytosis

0046872:metal ion binding

0001618:virus receptor activity

0009897:external side of plasma membrane

0019882:antigen processing and presentation

0019062:virion attachment to host cell

0097323:B cell adhesion

0045087:innate immune response

PDB

2B6B ; 2IT5 ; 6GHV ; 1SL5 ; 2XR6 ; 1K9I ; 2IT6 ; 1SL4 ; 2XR5

Drugbank

KEGG

hsa:30835

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0004	Huo Xiang	藿香	Patchouli	Pogostemon cablin
H0958	Dang Shen	党参	Pilose asiabell	Codonopsis pilosula
H0173	Lu Hui	芦荟	Kulaso aloe dried juice	Aloe vera
H0572	Tu Huo Xiang	土藿香	Patchouli	Pogostemon cablin
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0669	Xie Bai	薤白	Longstamen onion	Allium macrostemon
H0357	Ren Shen	人参	Ginseng	Panax ginseng
H1153	Hai Shen	海参	Sea cucumber	Holothuria leucospilota
H0005	Huo Xiang Ye	藿香叶	Patchouli	Pogostemon cablin
H1010	Du Huo Xiang	杜藿香	Patchouli	Pogostemon cablin
H0549	Tian Zhu Huang	天竺黄	Chinese schinzostachyum tabasheer	Concretio silicea bambusae
H1120	Guang Huo Xiang	广藿香	Patchouli	Pogostemon cablin

Target Description

Related Compounds (Total: 2)

Related Herbs (Total: 13)