HIT-result

Type	Detail
Target ID	T61GAB
Protein Name	Interleukin-1 receptor antagonist protein
Uniprot ID	P18510
Protein Name Alias	IL-1RN; IL-1ra; IRAP; ICIL-1RA; IL1 inhibitor; Anakinra
Gene ID	3557
Gene Symbol	IL1RN
Gene Alias	IL1F3; IL1RA
TTD	NA
Pfam	PF00340
GO	0070062:extracellular exosome 0005615:extracellular space 0006953:acute-phase response 0002437:inflammatory response to antigenic stimulus 2000660:negative regulation of interleukin-1-mediated signaling pathway 0005152:interleukin-1 receptor antagonist activity 0045353:interleukin-1 type II receptor antagonist activity 0070498:interleukin-1-mediated signaling pathway 0005151:interleukin-1, type II receptor binding 0006629:lipid metabolic process 0005886:plasma membrane 0005737:cytoplasm 0005150:interleukin-1, type I receptor binding 0005125:cytokine activity 0005149:interleukin-1 receptor binding 0051384:response to glucocorticoid 0045352:interleukin-1 type I receptor antagonist activity 0006955:immune response 0019221:cytokine-mediated signaling pathway 0006954:inflammatory response 0030073:insulin secretion 0034115:negative regulation of heterotypic cell-cell adhesion
PDB	1IRP ; 1ILR ; 1ITN ; 1IRA ; 1ILT ; 2IRT
Drugbank	DB06372
KEGG	hsa:3557

Target Description