Target Description
| Type | Detail |
|---|---|
| Target ID | T64SK3 |
| Protein Name | Programmed cell death 1 ligand 2 |
| Uniprot ID |
Q9BQ51 |
| Protein Name Alias | PD-1 ligand 2; PD-L2; PDCD1 ligand 2; Programmed death ligand 2; Butyrophilin B7-DC; B7-DC; CD antigen CD273 |
| Gene ID |
80380 |
| Gene Symbol | PDCD1LG2 |
| Gene Alias | B7DC; CD273; PDCD1L2; PDL2 |
| TTD | T50035: Patented target |
| Pfam | PF08205 |
| GO |
0071222:cellular response to lipopolysaccharide
0006955:immune response 0032693:negative regulation of interleukin-10 production 0042130:negative regulation of T cell proliferation 0016021:integral component of membrane 0046007:negative regulation of activated T cell proliferation 0042102:positive regulation of T cell proliferation 0031295:T cell costimulation 0009897:external side of plasma membrane 0005576:extracellular region 0007166:cell surface receptor signaling pathway 0012505:endomembrane system 0002250:adaptive immune response 0032689:negative regulation of interferon-gamma production 0005886:plasma membrane |
| PDB | 6UMT |
| Drugbank | NA |
| KEGG | hsa:80380 |
