HIT-result

Type	Detail
Target ID	T67LL5
Protein Name	Regulatory-associated protein of mTOR
Uniprot ID	Q8N122
Protein Name Alias	Raptor; p150 target of rapamycin (TOR)-scaffold protein
Gene ID	57521
Gene Symbol	RPTOR
Gene Alias	KIAA1303; RAPTOR
TTD	T58772: Clinical Trial target
Pfam	PF02985 ; PF00400 ; PF14538
GO	0030425:dendrite 0007050:cell cycle arrest 0071233:cellular response to leucine 0005829:cytosol 1900034:regulation of cellular response to heat 0001938:positive regulation of endothelial cell proliferation 0001558:regulation of cell growth 0032008:positive regulation of TOR signaling 0001003:RNA polymerase III type 2 promoter sequence-specific DNA binding 0045945:positive regulation of transcription by RNA polymerase III 0030674:protein-macromolecule adaptor activity 0030295:protein kinase activator activity 1900087:positive regulation of G1/S transition of mitotic cell cycle 0005765:lysosomal membrane 0031929:TOR signaling 0019901:protein kinase binding 0044877:protein-containing complex binding 0031931:TORC1 complex 0005764:lysosome 0034198:cellular response to amino acid starvation 0001002:RNA polymerase III type 1 promoter sequence-specific DNA binding 0071889:14-3-3 protein binding 0001006:RNA polymerase III type 3 promoter sequence-specific DNA binding 0030291:protein serine/threonine kinase inhibitor activity 0031669:cellular response to nutrient levels 0001156:TFIIIC-class transcription factor complex binding 0071902:positive regulation of protein serine/threonine kinase activity 0030307:positive regulation of cell growth 0010800:positive regulation of peptidyl-threonine phosphorylation 0005737:cytoplasm 0010494:cytoplasmic stress granule 0071230:cellular response to amino acid stimulus 0016032:viral process 0038202:TORC1 signaling 0005654:nucleoplasm 0043025:neuronal cell body 0008361:regulation of cell size 0033138:positive regulation of peptidyl-serine phosphorylation 0010506:regulation of autophagy 0009267:cellular response to starvation 0016241:regulation of macroautophagy
PDB	6SB0 ; 5H64 ; 6BCU ; 6BCX ; 6SB2 ; 6U62
Drugbank	NA
KEGG	hsa:57521

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Name: Aicar

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens