Target Description

Type Detail
Target ID T67ZCS
Protein Name NLR family CARD domain-containing protein 4
Uniprot ID Q9NPP4
Protein Name Alias CARD, LRR, and NACHT-containing protein;  Clan protein;  Caspase recruitment domain-containing protein 12;  Ice protease-activating factor;  Ipaf
Gene ID 58484
Gene Symbol NLRC4
Gene Alias CARD12;  CLAN;  CLAN1;  IPAF
TTD NA
Pfam PF17889 ; PF00619 ; PF05729
GO
0042802:identical protein binding

0042981:regulation of apoptotic process

0010954:positive regulation of protein processing

0072557:IPAF inflammasome complex

0016045:detection of bacterium

0006915:apoptotic process

0097202:activation of cysteine-type endopeptidase activity

0051092:positive regulation of NF-kappaB transcription factor activity

0002218:activation of innate immune response

0061133:endopeptidase activator activity

0005829:cytosol

0005524:ATP binding

0000287:magnesium ion binding

0070269:pyroptosis

0006954:inflammatory response

0043065:positive regulation of apoptotic process

0032731:positive regulation of interleukin-1 beta production

0042803:protein homodimerization activity

0006919:activation of cysteine-type endopeptidase activity involved in apoptotic process

0042742:defense response to bacterium

0089720:caspase binding

0051260:protein homooligomerization

0045087:innate immune response

PDB 6K8J ; 6N1I ; 6MKS
Drugbank NA
KEGG hsa:58484

Related Compounds  (Total: 1)

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C0322
Name: Prasterone


Related Herbs  (Total: 2)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens