Target Description

Type Detail
Target ID T68PGG
Protein Name Solute carrier family 12 member 5
Uniprot ID Q9H2X9
Protein Name Alias Electroneutral potassium-chloride cotransporter 2;  K-Cl cotransporter 2;  hKCC2;  Neuronal K-Cl cotransporter
Gene ID 57468
Gene Symbol SLC12A5
Gene Alias KCC2;  KIAA1176
TTD T22302: Research target
Pfam PF03522 ; PF00324
GO
0035264:multicellular organism growth

0007612:learning

0006811:ion transport

0006873:cellular ion homeostasis

0007268:chemical synaptic transmission

0071944:cell periphery

0060996:dendritic spine development

0015379:potassium:chloride symporter activity

0015108:chloride transmembrane transporter activity

0006884:cell volume homeostasis

0019901:protein kinase binding

0043005:neuron projection

0005887:integral component of plasma membrane

0005886:plasma membrane

0016021:integral component of membrane

0030644:cellular chloride ion homeostasis

0040040:thermosensory behavior

0042493:response to drug

0045202:synapse

0043025:neuronal cell body

1990573:potassium ion import across plasma membrane

0006971:hypotonic response

1902476:chloride transmembrane transport

0055064:chloride ion homeostasis

0055075:potassium ion homeostasis

PDB 6M23 ; 7D8Z
Drugbank DB00761 ; DB00887
KEGG hsa:57468

Related Compounds  (Total: 2)

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C0012
Name: Diazepam
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C0280
Name: Oxytocin


Related Herbs  (Total: 2)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0847 Zi He Che紫河车 Human placentaHomo sapiens