HIT-result

Type	Detail
Target ID	T70DWW
Protein Name	C-X-C chemokine receptor type 1
Uniprot ID	P25024
Protein Name Alias	CXC-R1; CXCR-1; CDw128a; High affinity interleukin-8 receptor A; IL-8R A; IL-8 receptor type 1; CD antigen CD181
Gene ID	3577
Gene Symbol	CXCR1
Gene Alias	CMKAR1; IL8RA
TTD	T00884: Successful target
Pfam	PF00001
GO	0030667:secretory granule membrane 0004950:chemokine receptor activity 0019959:interleukin-8 binding 0007204:positive regulation of cytosolic calcium ion concentration 0004918:interleukin-8 receptor activity 0006955:immune response 0031623:receptor internalization 0019957:C-C chemokine binding 0016493:C-C chemokine receptor activity 0002407:dendritic cell chemotaxis 0005886:plasma membrane 0060326:cell chemotaxis 0016021:integral component of membrane 0043312:neutrophil degranulation 0004930:G protein-coupled receptor activity 0009897:external side of plasma membrane 0007186:G protein-coupled receptor signaling pathway 0019722:calcium-mediated signaling 0007166:cell surface receptor signaling pathway 0030593:neutrophil chemotaxis
PDB	1ILP ; 1ILQ ; 2LNL
Drugbank	DB01009
KEGG	hsa:3577

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens

Target Description