HIT-result

Type	Detail
Target ID	T71XEF
Protein Name	fMet-Leu-Phe receptor
Uniprot ID	P21462
Protein Name Alias	fMLP receptor; N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor
Gene ID	2357
Gene Symbol	FPR1
Gene Alias	NA
TTD	T87831: Clinical Trial target
Pfam	PF00001
GO	0030667:secretory granule membrane 0016021:integral component of membrane 0050786:RAGE receptor binding 0101003:ficolin-1-rich granule membrane 0007186:G protein-coupled receptor signaling pathway 0002430:complement receptor mediated signaling pathway 0035577:azurophil granule membrane 0005886:plasma membrane 0004930:G protein-coupled receptor activity 0004875:complement receptor activity 0001664:G protein-coupled receptor binding 0005737:cytoplasm 0004982:N-formyl peptide receptor activity 0007188:adenylate cyclase-modulating G protein-coupled receptor signaling pathway 0043312:neutrophil degranulation 0019221:cytokine-mediated signaling pathway 0007263:nitric oxide mediated signal transduction 0006935:chemotaxis 0007200:phospholipase C-activating G protein-coupled receptor signaling pathway 0006954:inflammatory response 0005124:scavenger receptor binding 0000187:activation of MAPK activity 0007165:signal transduction 0007204:positive regulation of cytosolic calcium ion concentration
PDB	NA
Drugbank	DB00716
KEGG	hsa:2357

Target Description