HIT-result

Type	Detail
Target ID	T72IYV
Protein Name	Platelet-activating factor receptor
Uniprot ID	P25105
Protein Name Alias	PAF-R; PAFr
Gene ID	5724
Gene Symbol	PTAFR
Gene Alias	PAFR
TTD	T87023: Successful target
Pfam	PF00001
GO	0051019:mitogen-activated protein kinase binding 0030667:secretory granule membrane 0045776:negative regulation of blood pressure 0043315:positive regulation of neutrophil degranulation 0048015:phosphatidylinositol-mediated signaling 1904300:positive regulation of transcytosis 1904317:cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine 1904058:positive regulation of sensory perception of pain 0071398:cellular response to fatty acid 0032755:positive regulation of interleukin-6 production 0001875:lipopolysaccharide immune receptor activity 0006955:immune response 0045907:positive regulation of vasoconstriction 1902943:positive regulation of voltage-gated chloride channel activity 0070821:tertiary granule membrane 0005543:phospholipid binding 1904303:positive regulation of maternal process involved in parturition 0016021:integral component of membrane 1904306:positive regulation of gastro-intestinal system smooth muscle contraction 0005887:integral component of plasma membrane 0045727:positive regulation of translation 0009609:response to symbiotic bacterium 0001530:lipopolysaccharide binding 0005886:plasma membrane 0071320:cellular response to cAMP 0007567:parturition 0045028:G protein-coupled purinergic nucleotide receptor activity 0071258:cellular response to gravity 0048661:positive regulation of smooth muscle cell proliferation 0043312:neutrophil degranulation 0004930:G protein-coupled receptor activity 0016020:membrane 0002693:positive regulation of cellular extravasation 0006954:inflammatory response 0032959:inositol trisphosphate biosynthetic process 0045056:transcytosis 0004992:platelet activating factor receptor activity 0032760:positive regulation of tumor necrosis factor production 0060333:interferon-gamma-mediated signaling pathway 0007186:G protein-coupled receptor signaling pathway 0006357:regulation of transcription by RNA polymerase II 0010863:positive regulation of phospholipase C activity 0006935:chemotaxis 0019221:cytokine-mediated signaling pathway 1903238:positive regulation of leukocyte tethering or rolling 0071548:response to dexamethasone 0060732:positive regulation of inositol phosphate biosynthetic process
PDB	2B0X
Drugbank	DB11614 ; DB02261 ; DB09166
KEGG	hsa:5724

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Name: Ginkgolide B

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H1051	Bai Guo	白果	Ginkgo nut	Ginkgo biloba