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Target Description
Type
Detail
Target ID
T77INT
Protein Name
Lymphotoxin-alpha
Uniprot ID
P01374
Protein Name Alias
LT-alpha; TNF-beta; Tumor necrosis factor ligand superfamily member 1
Gene ID
4049
Gene Symbol
LTA
Gene Alias
TNFB; TNFSF1
TTD
T85158: Clinical Trial target
Pfam
PF00229
GO
0006915:apoptotic process
0042493:response to drug
0005615:extracellular space
0006959:humoral immune response
0002925:positive regulation of humoral immune response mediated by circulating immunoglobulin
0002876:positive regulation of chronic inflammatory response to antigenic stimulus
0001666:response to hypoxia
0005164:tumor necrosis factor receptor binding
0005886:plasma membrane
0043065:positive regulation of apoptotic process
0048535:lymph node development
0005102:signaling receptor binding
0007584:response to nutrient
0007165:signal transduction
0005125:cytokine activity
0060252:positive regulation of glial cell proliferation
0032496:response to lipopolysaccharide
0032729:positive regulation of interferon-gamma production
0050830:defense response to Gram-positive bacterium
0033209:tumor necrosis factor-mediated signaling pathway
0048147:negative regulation of fibroblast proliferation
0007267:cell-cell signaling
PDB
4MXV
;
4MXW
;
1TNR
Drugbank
DB00005
KEGG
hsa:4049
Related Compounds (Total: 1)
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C1074
Name: solamargine
Related Herbs (Total: 0)
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Herb id
Chinese Pin Yin
Chinese Character
English Name
Latin Name