Target Description

Type Detail
Target ID T77INT
Protein Name Lymphotoxin-alpha
Uniprot ID P01374
Protein Name Alias LT-alpha;  TNF-beta;  Tumor necrosis factor ligand superfamily member 1
Gene ID 4049
Gene Symbol LTA
Gene Alias TNFB;  TNFSF1
TTD T85158: Clinical Trial target
Pfam PF00229
GO
0006915:apoptotic process

0042493:response to drug

0005615:extracellular space

0006959:humoral immune response

0002925:positive regulation of humoral immune response mediated by circulating immunoglobulin

0002876:positive regulation of chronic inflammatory response to antigenic stimulus

0001666:response to hypoxia

0005164:tumor necrosis factor receptor binding

0005886:plasma membrane

0043065:positive regulation of apoptotic process

0048535:lymph node development

0005102:signaling receptor binding

0007584:response to nutrient

0007165:signal transduction

0005125:cytokine activity

0060252:positive regulation of glial cell proliferation

0032496:response to lipopolysaccharide

0032729:positive regulation of interferon-gamma production

0050830:defense response to Gram-positive bacterium

0033209:tumor necrosis factor-mediated signaling pathway

0048147:negative regulation of fibroblast proliferation

0007267:cell-cell signaling

PDB 4MXV ; 4MXW ; 1TNR
Drugbank DB00005
KEGG hsa:4049

Related Compounds  (Total: 1)

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C1074
Name: solamargine


Related Herbs  (Total: 0)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name