HIT-result

Type	Detail
Target ID	T77ISA
Protein Name	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Uniprot ID	Q9Y3Q4
Protein Name Alias	NA
Gene ID	10021
Gene Symbol	HCN4
Gene Alias	NA
TTD	T30286: Research target
Pfam	PF08412 ; PF00027 ; PF00520
GO	0031226:intrinsic component of plasma membrane 0042391:regulation of membrane potential 0006812:cation transport 0098909:regulation of cardiac muscle cell action potential involved in regulation of contraction 0030552:cAMP binding 0034765:regulation of ion transmembrane transport 0035725:sodium ion transmembrane transport 0042802:identical protein binding 0006936:muscle contraction 0071805:potassium ion transmembrane transport 0071321:cellular response to cGMP 0005248:voltage-gated sodium channel activity 0098855:HCN channel complex 0086041:voltage-gated potassium channel activity involved in SA node cell action potential depolarization 0055117:regulation of cardiac muscle contraction 0098719:sodium ion import across plasma membrane 0005222:intracellular cAMP-activated cation channel activity 0086012:membrane depolarization during cardiac muscle cell action potential 1990573:potassium ion import across plasma membrane 0005886:plasma membrane 0008015:blood circulation 0005249:voltage-gated potassium channel activity 0086046:membrane depolarization during SA node cell action potential 0003254:regulation of membrane depolarization 0086091:regulation of heart rate by cardiac conduction 0086015:SA node cell action potential 0002027:regulation of heart rate 0071320:cellular response to cAMP 0048471:perinuclear region of cytoplasm
PDB	6GYO ; 2MNG ; 4KL1 ; 4NVP ; 3U11 ; 6GYN ; 4HBN ; 3OTF
Drugbank	NA
KEGG	hsa:10021

Target Description

Related Compounds (Total: 2)

Related Herbs (Total: 1)