Target Description

Type Detail
Target ID T81X6W
Protein Name Endoplasmin
Uniprot ID P14625
Protein Name Alias 94 kDa glucose-regulated protein;  GRP-94;  Heat shock protein 90 kDa beta member 1;  Tumor rejection antigen 1;  gp96 homolog
Gene ID 7184
Gene Symbol HSP90B1
Gene Alias GRP94;  TRA1
TTD T81311: Clinical Trial target
Pfam PF02518 ; PF00183
GO
0071682:endocytic vesicle lumen

0005634:nucleus

0070062:extracellular exosome

0034976:response to endoplasmic reticulum stress

0005925:focal adhesion

0016887:ATPase activity

0005789:endoplasmic reticulum membrane

0005829:cytosol

0030433:ubiquitin-dependent ERAD pathway

0044267:cellular protein metabolic process

0034975:protein folding in endoplasmic reticulum

0030970:retrograde protein transport, ER to cytosol

0006457:protein folding

0001666:response to hypoxia

0033018:sarcoplasmic reticulum lumen

0043687:post-translational protein modification

0006898:receptor-mediated endocytosis

0005509:calcium ion binding

0002224:toll-like receptor signaling pathway

0005524:ATP binding

0005783:endoplasmic reticulum

0050750:low-density lipoprotein particle receptor binding

0048471:perinuclear region of cytoplasm

0030496:midbody

0051208:sequestering of calcium ion

0031247:actin rod assembly

0015031:protein transport

0051082:unfolded protein binding

0036500:ATF6-mediated unfolded protein response

0016020:membrane

0003723:RNA binding

0032991:protein-containing complex

0042470:melanosome

0062023:collagen-containing extracellular matrix

0005576:extracellular region

0043666:regulation of phosphoprotein phosphatase activity

0019221:cytokine-mediated signaling pathway

0071318:cellular response to ATP

0019903:protein phosphatase binding

0043066:negative regulation of apoptotic process

0005788:endoplasmic reticulum lumen

PDB 4NH9
Drugbank DB03758 ; DB03719 ; DB08465 ; DB02103 ; DB00615 ; DB08464 ; DB02935 ; DB02424 ; DB09130
KEGG hsa:7184

Related Compounds  (Total: 2)

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C0919
Name: Arctigenin
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C1265
Name: Curcumin


Related Herbs  (Total: 18)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0731 Ye Mei Gui Guo野玫瑰果 RosehipsRosa canina
H0142 Liang Jiang良姜 NAAlpinia officinarum
H0139 Lian Qiao连翘 Weeping forsythiaForsythia suspensa
H0614 Wu Zhao Long五爪龙 Cairo morninggloryIpomoea cairica
H0710 Yuan Hua Tiao芫花条 stem of lilac daphneDaphne genkwa
H0185 Luo Shi Teng络石藤 Chinese star jasmineTrachelospermum jasminoides
H0708 Yuan Hua Gen芫花根 Lilac daphne rootDaphne genkwa
H1093 Gao Liang Jiang You高良姜油 Lesser galangalAlpinia officinarum
H0146 Liao Ge Wang了哥王 NAWikstroemia indica
H0707 Yuan Hua芫花 Lilac daphneDaphne genkwa
H0556 Tie Xian Cao铁线草 NAAdiantum capillus-veneris
H0289 Niu Bang Zi牛蒡子 Great burdock fruitArctium lappa
H0895 Chuan Yu Jin川郁金 TurmericCurcuma longa
H0711 Yuan Hua Zhi Tiao芫花枝条 stem of lilac daphneDaphne genkwa
H0918 Cu Yuan Hua醋芫花 Lilac daphneDaphne genkwa
H0028 Jiang Huang姜黄 Common turmericCurcuma longa
H1092 Gao Liang Jiang高良姜 Lesser galangalAlpinia officinarum
H0761 Yu Jin郁金 AromaticTurmericCurcuma aromatica