HIT-result

Type	Detail
Target ID	T83H2N
Protein Name	DNA damage-inducible transcript 4 protein
Uniprot ID	Q9NX09
Protein Name Alias	HIF-1 responsive protein RTP801; Protein regulated in development and DNA damage response 1; REDD-1
Gene ID	54541
Gene Symbol	DDIT4
Gene Alias	REDD1; RTP801
TTD	T83561: Clinical Trial target
Pfam	PF07809
GO	0030182:neuron differentiation 0042771:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 0045820:negative regulation of glycolytic process 0071549:cellular response to dexamethasone stimulus 0005829:cytosol 1902532:negative regulation of intracellular signal transduction 0032984:protein-containing complex disassembly 0032006:regulation of TOR signaling 0051607:defense response to virus 0048011:neurotrophin TRK receptor signaling pathway 0001666:response to hypoxia 0071889:14-3-3 protein binding 0007420:brain development 0006915:apoptotic process 0001764:neuron migration 0072593:reactive oxygen species metabolic process 0010801:negative regulation of peptidyl-threonine phosphorylation 1901216:positive regulation of neuron death 0032007:negative regulation of TOR signaling 0005737:cytoplasm 0033137:negative regulation of peptidyl-serine phosphorylation 0005739:mitochondrion
PDB	3LQ9
Drugbank	NA
KEGG	hsa:54541

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0697	Ya Ma Zi	亚麻子	Common flax seed	Linum usitatissimum
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0761	Yu Jin	郁金	AromaticTurmeric	Curcuma aromatica

Target Description