HIT-result

Target Description

Type	Detail
Target ID	T83VW4
Protein Name	Myelin basic protein
Uniprot ID	P02686
Protein Name Alias	MBP; Myelin A1 protein; Myelin membrane encephalitogenic protein
Gene ID	4155
Gene Symbol	MBP
Gene Alias	NA
TTD	T54761: Clinical Trial target
Pfam	PF01669
GO	0043209:myelin sheath 0007417:central nervous system development 0007399:nervous system development 0009636:response to toxic substance 0032991:protein-containing complex 0033269:internode region of axon 0000165:MAPK cascade 0009986:cell surface 0032755:positive regulation of interleukin-6 production 0007268:chemical synaptic transmission 0061024:membrane organization 0043025:neuronal cell body 0019911:structural constituent of myelin sheath 0005829:cytosol 0005516:calmodulin binding 0045202:synapse 0005886:plasma membrane 0043218:compact myelin 0008366:axon ensheathment 0071944:cell periphery 0007605:sensory perception of sound 1904685:positive regulation of metalloendopeptidase activity 2000343:positive regulation of chemokine (C-X-C motif) ligand 2 production 0035633:maintenance of blood-brain barrier 0005634:nucleus 0002020:protease binding 0006955:immune response 0042552:myelination 0021762:substantia nigra development 0034115:negative regulation of heterotypic cell-cell adhesion
PDB	1K2D ; 1QCL ; 1YMM ; 1ZGL ; 1FV1 ; 1HQR ; 1BX2
Drugbank	NA
KEGG	hsa:4155

Type

Detail

Target ID

T83VW4

Protein Name

Myelin basic protein

Uniprot ID

P02686

Protein Name Alias

MBP; Myelin A1 protein; Myelin membrane encephalitogenic protein

Gene ID

4155

Gene Symbol

MBP

Gene Alias

TTD

T54761: Clinical Trial target

Pfam

PF01669

0043209:myelin sheath

0007417:central nervous system development

0007399:nervous system development

0009636:response to toxic substance

0032991:protein-containing complex

0033269:internode region of axon

0000165:MAPK cascade

0009986:cell surface

0032755:positive regulation of interleukin-6 production

0007268:chemical synaptic transmission

0061024:membrane organization

0043025:neuronal cell body

0019911:structural constituent of myelin sheath

0005829:cytosol

0005516:calmodulin binding

0045202:synapse

0005886:plasma membrane

0043218:compact myelin

0008366:axon ensheathment

0071944:cell periphery

0007605:sensory perception of sound

1904685:positive regulation of metalloendopeptidase activity

2000343:positive regulation of chemokine (C-X-C motif) ligand 2 production

0035633:maintenance of blood-brain barrier

0005634:nucleus

0002020:protease binding

0006955:immune response

0042552:myelination

0021762:substantia nigra development

0034115:negative regulation of heterotypic cell-cell adhesion

PDB

1K2D ; 1QCL ; 1YMM ; 1ZGL ; 1FV1 ; 1HQR ; 1BX2

Drugbank

KEGG

hsa:4155

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0064	Jin Yin Hua	金银花	Japanese honeysuckle	Lonicera japonica
H1055	Bai Guo Ren	白果仁	ginkgo	Ginkgo biloba
H0125	Lai Fu	莱菔	Garden radish	Raphanus sativus
H0697	Ya Ma Zi	亚麻子	Common flax seed	Linum usitatissimum
H0750	Yin Xing Ye	银杏叶	Folium ginkgo	Ginkgo biloba
H0370	Ru Xiang	乳香	Olibanum	Boswellia carterii
H0126	Lai Fu Zi	莱菔子	Garden radish seed	Raphanus sativus
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0354	Ren Dong Teng	忍冬藤	Japanese honeysuckle vine	Lonicera japonica
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0466	Cai Fu Zi	菜菔子	Semen raphani	Raphanus sativus
H0035	Bai Su Zi	白苏子	Common perilla fruit	Perilla frutescens
H0065	Jin Yin Hua Ti Qu Ye	金银花提取液	Japanese honeysuckle	Lonicera japonica
H1051	Bai Guo	白果	Ginkgo nut	Ginkgo biloba
H0003	Huo Ma Ren	火麻仁	Hemp fimble seed	Cannabis sativa
H0204	Ma Ren	麻仁	NA	Cannabis sativa

Target Description

Related Compounds (Total: 3)

Related Herbs (Total: 16)