Target Description

Type Detail
Target ID T83Y39
Protein Name Fructose-2,6-bisphosphatase TIGAR
Uniprot ID Q9NQ88
Protein Name Alias EC 3.1.3.46;  TP53-induced glycolysis and apoptosis regulator;  TP53-induced glycolysis regulatory phosphatase
Gene ID 57103
Gene Symbol TIGAR
Gene Alias C12orf5
TTD NA
Pfam PF00300
GO
0005634:nucleus

2000378:negative regulation of reactive oxygen species metabolic process

0004331:fructose-2,6-bisphosphate 2-phosphatase activity

0002931:response to ischemia

0005829:cytosol

0071456:cellular response to hypoxia

0071279:cellular response to cobalt ion

1902153:regulation of response to DNA damage checkpoint signaling

1901525:negative regulation of mitophagy

0006915:apoptotic process

1901215:negative regulation of neuron death

0010332:response to gamma radiation

0006914:autophagy

0060576:intestinal epithelial cell development

0005741:mitochondrial outer membrane

0030388:fructose 1,6-bisphosphate metabolic process

0004083:bisphosphoglycerate 2-phosphatase activity

0045820:negative regulation of glycolytic process

0010666:positive regulation of cardiac muscle cell apoptotic process

1903301:positive regulation of hexokinase activity

0006003:fructose 2,6-bisphosphate metabolic process

0005737:cytoplasm

0045739:positive regulation of DNA repair

0043069:negative regulation of programmed cell death

1904024:negative regulation of glucose catabolic process to lactate via pyruvate

0043456:regulation of pentose-phosphate shunt

0006974:cellular response to DNA damage stimulus

0009410:response to xenobiotic stimulus

PDB 3DCY
Drugbank NA
KEGG hsa:57103

Related Compounds  (Total: 1)

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C0267
Name: Oroxylin A


Related Herbs  (Total: 15)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0530 Tao Ren Shuang桃仁霜 Peach kernelPrunus persica
H1251 Huang Qin黄芩 Root of Baikal skullcaapScutellaria baicalensis
H1017 Du Zhong Ye杜仲叶 Eucommia leafEucommia ulmoides
H1016 Du Zhong Tan杜仲炭 EucommiaEucommia ulmoides
H0310 Pian Qin片芩 Scutellaria amoenaScutellaria baicalensis
H1253 Huang Qin Jin Gao Fen黄芩浸膏粉 Extract of root of Baikal skullcaapScutellaria baicalensis
H0529 Tao Ren桃仁 Peach kernelPrunus persica
H1015 Du Zhong杜仲 EucommiaEucommia ulmoides
H1254 Huang Qin Tan黄芩炭 Extract of root of Baikal skullcaapScutellaria baicalensis
H0626 Xi Nan Huang Qin西南黄芩 Yunnan skullcapScutellaria amoena
H0527 Tao PeachPrunus persica
H1252 Huang Qin Jin Gao黄芩浸膏 Extract of root of Baikal skullcaapScutellaria baicalensis
H0531 Tao Zhi桃枝 Peach juvenile branchPrunus persica
H0891 Chuan Xin Lian Ye穿心莲叶 Powder of green chiretta leavesAndrographis herba
H0270 Mu Hu Die木蝴蝶 Indian trumpetflowerOroxylum indicum