HIT-result

Type	Detail
Target ID	T85D16
Protein Name	Inositol-trisphosphate 3-kinase A
Uniprot ID	P23677
Protein Name Alias	EC 2.7.1.127; Inositol 1,4,5-trisphosphate 3-kinase A; IP3 3-kinase A; IP3K A; InsP 3-kinase A
Gene ID	3706
Gene Symbol	ITPKA
Gene Alias	NA
TTD	NA
Pfam	PF03770
GO	0006020:inositol metabolic process 0008440:inositol-1,4,5-trisphosphate 3-kinase activity 0005524:ATP binding 0043197:dendritic spine 0030036:actin cytoskeleton organization 0005829:cytosol 0043647:inositol phosphate metabolic process 0005516:calmodulin binding 0031267:small GTPase binding 0061003:positive regulation of dendritic spine morphogenesis 0004683:calmodulin-dependent protein kinase activity 0005737:cytoplasm 0097062:dendritic spine maintenance 0046854:phosphatidylinositol phosphorylation 0048167:regulation of synaptic plasticity 0005634:nucleus 0000828:inositol hexakisphosphate kinase activity 0032958:inositol phosphate biosynthetic process 0007165:signal transduction 0016301:kinase activity
PDB	1W2C ; 4UPU ; 1W2D ; 1W2F
Drugbank	DB04395 ; DB03401 ; DB01863
KEGG	hsa:3706

Target Description