HIT-result

Type	Detail
Target ID	T85H5E
Protein Name	N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase
Uniprot ID	O15527
Protein Name Alias	EC 3.2.2.-; apurinic or apyrimidinic site; AP lyase; EC 4.2.99.18
Gene ID	4968
Gene Symbol	OGG1
Gene Alias	MMH; MUTM; OGH1
TTD	T92189: Research target
Pfam	PF07934 ; PF00730
GO	0006355:regulation of transcription, DNA-templated 0032357:oxidized purine DNA binding 0032991:protein-containing complex 0003684:damaged DNA binding 0006974:cellular response to DNA damage stimulus 0042493:response to drug 1901291:negative regulation of double-strand break repair via single-strand annealing 0004519:endonuclease activity 0006285:base-excision repair, AP site formation 0043066:negative regulation of apoptotic process 0002526:acute inflammatory response 0005829:cytosol 0071276:cellular response to cadmium ion 0008534:oxidized purine nucleobase lesion DNA N-glycosylase activity 0034039:8-oxo-7,8-dihydroguanine DNA N-glycosylase activity 0051593:response to folic acid 0009314:response to radiation 0005654:nucleoplasm 0032355:response to estradiol 0006287:base-excision repair, gap-filling 0016363:nuclear matrix 0016607:nuclear speck 0033683:nucleotide-excision repair, DNA incision 0009416:response to light stimulus 0005634:nucleus 0005759:mitochondrial matrix 0045471:response to ethanol 0006979:response to oxidative stress 0140078:class I DNA-(apurinic or apyrimidinic site) endonuclease activity 0008017:microtubule binding 0045007:depurination 0006284:base-excision repair 0007568:aging 0045008:depyrimidination
PDB	1M3H ; 1M3Q ; 1FN7 ; 2I5W ; 2XHI ; 6W0M ; 6W0R ; 2NOL ; 1YQL ; 2NOI ; 1YQK ; 1YQM ; 1LWY ; 1LWV ; 1N3C ; 1YQR ; 2NOE ; 1KO9 ; 2NOB ; 1HU0 ; 6RLW ; 1N3A ; 2NOF ; 2NOZ ; 3IH7 ; 1EBM ; 1LWW ; 3KTU ; 5AN4 ; 6W13 ; 1N39 ; 2NOH
Drugbank	NA
KEGG	hsa:4968

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Name: vitamin c

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens