Target Description

Type Detail
Target ID T87F4H
Protein Name Insulin-induced gene 1 protein
Uniprot ID O15503
Protein Name Alias INSIG-1
Gene ID 3638
Gene Symbol INSIG1
Gene Alias NA
TTD NA
Pfam PF07281
GO
0036316:SREBP-SCAP complex retention in endoplasmic reticulum

0032937:SREBP-SCAP-Insig complex

0005783:endoplasmic reticulum

0005789:endoplasmic reticulum membrane

0006641:triglyceride metabolic process

0042472:inner ear morphogenesis

0032933:SREBP signaling pathway

0060363:cranial suture morphogenesis

0060021:roof of mouth development

1901303:negative regulation of cargo loading into COPII-coated vesicle

0036315:cellular response to sterol

0045717:negative regulation of fatty acid biosynthetic process

0070862:negative regulation of protein exit from endoplasmic reticulum

0008142:oxysterol binding

0010894:negative regulation of steroid biosynthetic process

0042632:cholesterol homeostasis

0042474:middle ear morphogenesis

0016126:sterol biosynthetic process

0032869:cellular response to insulin stimulus

0006695:cholesterol biosynthetic process

0045599:negative regulation of fat cell differentiation

PDB 4J81
Drugbank NA
KEGG hsa:3638

Related Compounds  (Total: 1)

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C0403
Name: Silibinin


Related Herbs  (Total: 3)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0095 Gou Qi Zi枸杞子 Chinese wolfberry fruitLycium chinense
H0484 Shui Fei Ji水飞蓟 St marysSilybum marianum
H0094 Gou Qi枸杞 Chinese wolfberry fruitLycium chinense